Coronary angiography using second-generation dual source computed tomography: Feasibility of low dose and low flow rate to achieve appropriate individual contrast enhancement using a test bolus-based contrast medium protocol-A CONSORT compliant article

Medicine
Xiaomei ZhuLijun Tang

Abstract

Improved contrast enhancement consistency can be achieved using an individualized contrast media (CM) protocol. This study aimed to assess the feasibility of a low-dose, low-flow rate CM protocol to achieve appropriate individual contrast enhancement using a newly advocated individualized test bolus-based protocol for second-generation dual-source computed tomography angiography.CM containing iodine (370 mg I/mL) was used in this study. A CM flow rate of 3.5 mL/s for patients with a body mass index (BMI) <25.0 kg/m, and 4.5 mL/s for those with BMI ≥25.0 kg/m was used in group 1 (n = 189). An individualized test-bolus based contrast injection protocol was then derived from the information gained from the test bolus and coronary enhancements in group 1. The proposed individualized test-bolus based CM injection protocol was applied in group 2 (n = 219). Ascending aortic attenuations (AAo) were measured and compared with both groups.The contrast enhancement consistency of AAo in group 2 improved significantly (31.8 vs 56.3 Hounsfield units [HU]; P < .001). The number of patients in group 2 with a contrast flow rate ≤3 mL/s was 63 (28.8%), with 77 (35.2%) using a contrast dose ≤40 mL. In group 2, no significant differences in mean A...Continue Reading

References

Mar 1, 1995·Journal of Computer Assisted Tomography·L van HoeL Mertens
Oct 21, 2003·Investigative Radiology·Christoph R BeckerMaximilian F Reiser
Sep 21, 2006·AJR. American Journal of Roentgenology·Filippo CademartiriGabriel P Krestin
Jun 20, 2008·AJR. American Journal of Roentgenology·Xiaolu FeiKuncheng Li
Mar 24, 2009·AJR. American Journal of Roentgenology·Robert DonninoMonvadi B Srichai
Feb 24, 2011·AJR. American Journal of Roentgenology·Markus WeiningerU Joseph Schoepf
Oct 5, 2011·The International Journal of Cardiovascular Imaging·Xiaomei ZhuLijun Tang
May 24, 2012·The International Journal of Cardiovascular Imaging·Wen Jie YangFu Hua Yan
Dec 6, 2014·Investigative Radiology·Michael M LellHubertus Pietsch
Feb 26, 2015·AJR. American Journal of Roentgenology·Bruce PreciousJonathon Leipsic
Mar 11, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Akira Sato, Kazutaka Aonuma
Mar 7, 2017·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Casper MihlMarco Das

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BETA
coronary artery bypass

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SPSS

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