Coronary artery aneurysm and thrombosis following chronic ephedra use

International Journal of Cardiology
Casey M FlanaganMark C P Haigney

Abstract

Ephedra, also known as Ma Huang, was commonly used to enhance athletic performance, "fat burning", and weight loss before its removal from the United States in April 2004 due to acute adverse health reactions including lethal arrhythmias, stroke, vasoconstriction, and myocardial infarction. We report the case of a 29-year-old patient with acute myocardial infarction, secondary to coronary artery aneurysms and thrombosis who reported use of Ma Huang, Xenadrine(r)RFA, and Hydroxycut at recommended dosages for a combined total of approximately 2 years. Other causes of coronary artery aneurysm and hypercoagulability were ruled out. Our case exemplifies the long-term (as opposed to acute) danger of ephedrine products and the first case of coronary artery aneurysm associated with its use.

References

Nov 7, 1999·Journal of the American College of Cardiology·D KrügerA Sheikhzadeh
Aug 19, 2004·Cardiology in Review·Kathleen BrennanAbdou Elhendy
May 11, 2005·Circulation·Aaron SatranTimothy D Henry
Dec 3, 2008·International Journal of Cardiology·Andrew J S Coats

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Citations

Feb 19, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Fang-Hao ZhengJia-Bo Luo
Jan 5, 2013·Journal of Ethnopharmacology·Ellie J Y KimGeorge Q Li
Sep 30, 2014·Clinical Therapeutics·Bill J GurleySheila L Thomas
Jul 2, 2016·The Journal of Dermatological Treatment·Shefton ParkerCharlie C Xue
Dec 19, 2015·International Journal of Immunopathology and Pharmacology·Graziano RiccioniTonino Bucciarelli
Jun 17, 2011·Journal of Pharmacy Practice·Jivan MoaddebMicheal B Bevins

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