Coronary calcium screening with dual-source CT: reliability of ungated, high-pitch chest CT in comparison with dedicated calcium-scoring CT

European Radiology
Antoine HuttMartine Remy-Jardin

Abstract

To investigate the reliability of ungated, high-pitch dual-source CT for coronary artery calcium (CAC) screening. One hundred and eighty-five smokers underwent a dual-source CT examination with acquisition of two sets of images during the same session: (a) ungated, high-pitch and high-temporal resolution acquisition over the entire thorax (i.e., chest CT); (b) prospectively ECG-triggered acquisition over the cardiac cavities (i.e., cardiac CT). Sensitivity and specificity of chest CT for detecting positive CAC scores were 96.4 % and 100 %, respectively. There was excellent inter-technique agreement for determining the quantitative CAC score (ICC = 0.986). The mean difference between the two techniques was 11.27, representing 1.81 % of the average of the two techniques. The inter-technique agreement for categorizing patients into the four ranks of severity was excellent (weighted kappa = 0.95; 95 % CI 0.93-0.98). The inter-technique differences for quantitative CAC scores did not correlate with BMI (r = 0.05, p = 0.575) or heart rate (r = -0.06, p = 0.95); 87.2 % of them were explained by differences at the level of the right coronary artery (RCA: 0.8718; LAD: 0.1008; LCx: 0.0139; LM: 0.0136). Ungated, high-pitch dual-source CT ...Continue Reading

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Citations

May 3, 2016·Journal of Cardiovascular Computed Tomography·Veit SandfortDavid A Bluemke
Dec 3, 2017·European Radiology·Christoph SchabelMalte N Bongers
Nov 14, 2018·Journal of Computer Assisted Tomography·Nagina MalguriaElliot K Fishman
Jun 12, 2018·Chest·Surya P BhattUNKNOWN COPDGene Investigators
Apr 16, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jin Young KimByoung Wook Choi

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