Sep 1, 1977

Coronary embolism and myocardial infarction associated with nonbacterial thrombotic endocarditis

American Journal of Clinical Pathology
A O Fayemi, L M Deppisch

Abstract

Six cases of coronary embolism and myocardial infarction associated with nonbacterial thrombotic endocarditis were seen at the Mount Sinai Hospital over a ten-year period. Every patient had an underlying malignant neoplasm. The vegetations were found on aortic, mitral, tricuspid and pulmonic valves and were located on the free or closure margins. The clinical diagnosis of this condition is difficult because of simultaneous embolization to the brain, causing widespread neurologic symptoms, but could be made by electrocardiographic and serum enzyme studies. Myocardial infarction caused the deaths of three patients. The relationship between nonbacterial thrombotic endocarditis, hypercoagulability, and disseminated intravascular coagulation is discussed.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Non-Infective Endocarditis
Neurologic Manifestations
Disseminated Intravascular Coagulation
Thrombophilia
Infective Endocarditis
Brain
Myocardium
Myocardial Infarction
Primary Malignant Neoplasm
Aorta

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.