PMID: 6451167Mar 1, 1981Paper

Coronary flow studies in patients with left ventricular hypertrophy of the hypertensive type. Evidence for an impaired coronary vascular reserve

The American Journal of Cardiology
A D PichardJ Meller

Abstract

Increased myocardial blood flow occurs in ventricular hypertrophy, but flow per 100 grams of myocardium remains normal. The increase in flow may be obtained at the expense of the existing coronary vascular reserve or by an increase in the vascular bed. The coronary vascular reserve was studied by analyzing the hyperemic reaction to selective injection of contrast agent into the coronary arteries in 25 patients: a control group (9 patients) with chest pain syndrome, normal coronary arteries and a normal left ventricle (Group I) and 16 patients with aortic stenosis, left ventricular hypertrophy and normal coronary arteries (Group II). The hyperemic response in Groups I and II was 73.3 +/- 2.2 and 65.8 +/- 9.1 percent, respectively (difference not significant). Group II was subdivided into two groups: Group IIA had five patients with a left ventricular mass of less than 200 g (mean 158.8 +/- 25.9); this group had a hyperemic response of 102.3 +/- 9.9 percent. Group IIB had 11 patients with a left ventricular mass of more than 200 g (mean 308.9 +/- 22.5) and a hyperemic response of 49.27 +/- 10.42 percent. The hyperemic response was correlated with the diastolic left ventricular-aortic gradient (r = +0.64, p less than 0.001), left ...Continue Reading

References

Jun 1, 1978·Circulation·T M McFarlandP D Stein
Jul 1, 1978·Circulation Research·D D O'KeefeE Shapkin
Mar 1, 1978·Circulation Research·H R WeissA K Sinha
Mar 1, 1978·Circulation Research·A WalstonJ C Greenfield
Jan 1, 1975·Japanese Heart Journal·H YamazakiY Nakamura
Jan 1, 1972·Circulation Research·G D BuckbergJ I Hoffman
Jan 1, 1968·British Heart Journal·W B Hood
Oct 1, 1967·Circulation·E L FallenR Gorlin
Sep 1, 1958·Circulation Research·L N KATZ, H FEINBERG
Feb 6, 1959·Annals of the New York Academy of Sciences·R E OLSON, D A PIATNEK
Mar 1, 1961·Annals of Internal Medicine·G G ROWEC W CRUMPTON
Mar 1, 1960·The American Journal of Cardiology·A J LINZBACH

❮ Previous
Next ❯

Citations

Feb 1, 1994·Cardiovascular Drugs and Therapy·R GistriP G Camici
Jan 1, 1983·Pharmacology & Therapeutics·W H Newman
Jan 1, 1989·Journal of the American College of Cardiology·J M Nicklas, S J Gips
Apr 1, 1995·Journal of the American College of Cardiology·O GurnéE Schroeder
Oct 1, 1989·The Annals of Thoracic Surgery·T FujiwaraF Kajiya
Apr 18, 1997·International Journal of Cardiology·A KranidisL Anthopoulos
May 1, 1991·Journal of the American College of Cardiology·J K GhaliY L Liao
Feb 1, 1983·Journal of the American College of Cardiology·L W KleinL E Teichholz
Mar 1, 1983·Journal of the American College of Cardiology·R Gorlin
Apr 1, 1984·Journal of the American College of Cardiology·L W KleinL E Teichholz
Jun 1, 1985·Journal of the American College of Cardiology·M VolpeM Condorelli
Feb 26, 2000·Journal of Internal Medicine·A NataliE Ferrannini
Nov 15, 1984·The New England Journal of Medicine·A G WassermanA M Ross
Oct 1, 1992·The New England Journal of Medicine·E D FrohlichB Massie
Jan 24, 2006·BMC Cardiovascular Disorders·Akinyemi AjeAyodele O Falase
Mar 25, 2000·Journal of Molecular and Cellular Cardiology·M P KingsburyD J Sheridan
Apr 1, 1995·Current Problems in Cardiology·M S Fenster, M D Feldman
Mar 12, 1990·The American Journal of Medicine·C K Francis
May 1, 1988·Progress in Cardiovascular Diseases·R J Bache
Jul 1, 1982·The American Journal of Cardiology·G R DreslinskiE D Frohlich
May 1, 1984·The American Journal of Cardiology·K KobayashiK Rakusan
Jun 1, 1986·The American Journal of Cardiology·E MarchantP Casanegra
Jun 11, 2004·Pacing and Clinical Electrophysiology : PACE·Okan ErdoganGultac Ozbay
Nov 25, 2000·Journal of the American College of Cardiology·D J Hildick-Smith, L M Shapiro
Feb 1, 1995·Journal of the American College of Cardiology·M F StoddardG T Morris
Jun 1, 1984·Journal of the American College of Cardiology·W W O'NeillR A Vogel
Feb 1, 1984·Journal of the American College of Cardiology·W K LaskeyJ W Hirshfeld
May 1, 1987·Journal of the American College of Cardiology·B H Lorell, W Grossman
Aug 1, 1986·Journal of the American College of Cardiology·L W KleinR H Helfant
Dec 1, 1984·The American Journal of Cardiology·K G PetersM L Marcus

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.