PMID: 6104171Jun 28, 1980Paper

Coronary-heart-disease risk and impaired glucose tolerance. The Whitehall study

J H FullerH Keen


In the Whitehall Study of 18,403 male civil servants aged 40--64 years, 7 1/2 year coronary-heart-disease (CHD) mortality has been examined in relation to blood-sugar concentration 2 h after a 50 g oral glucose load. CHD mortality was approximately doubled for subjects with inpaired glucose tolerance (IGT), defined as a blood-sugar above the 95th centile (greater than or equal to 96 mg/dl). There was no trend of CHD mortality with blood-sugar below the 95th centile. Within the IGT group, age, systolic blood-pressure, and ECG abnormality (Whitehall criteria) were significantly predictive of subsequent CHD mortality. These findings are relevant to discussions on the criteria for diabetes which include the definition of an IGT category with increased risk of large-vessel disease, but without the high risk of small-vessel disease as occurs in diabetes mellitus.


Jan 1, 1979·Journal of Chronic Diseases·K PyöräläP Siltanen
May 1, 1979·Diabetologia·H KeenK G Alberti
Oct 20, 1979·British Medical Journal·J H FullerY Stirling
Sep 1, 1979·Diabetologia·A G Cudworth
Jan 1, 1979·Journal of Chronic Diseases·J H FullerP J Hamilton
Jun 1, 1978·British Heart Journal·G RoseP McCartney
Sep 20, 1971·JAMA : the Journal of the American Medical Association·J Cornfield
Jan 1, 1968·Monograph Series·G A Rose, H Blackburn

❮ Previous
Next ❯


Feb 1, 1990·Diabetes/metabolism Reviews·F L Dunn
Mar 1, 1990·Diabetes/metabolism Reviews·P ZimmetH King
Dec 1, 1990·Diabetes/metabolism Reviews·K L RamaiyaK G Alberti
Sep 1, 1982·Diabetologia·W J Mutch, J M Stowers
Jan 1, 1985·Diabetologia·K FalholtL G Heding
Nov 1, 1983·Diabetologia
Sep 1, 1987·Diabetologia·M ModanA Lusky
Jan 1, 1991·European Journal of Clinical Pharmacology·A E PontiroliG Pozza
Jan 1, 1982·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·P D LangJ Vollmar
Jan 1, 1992·European Journal of Clinical Pharmacology·F PasanisiM Mancini
Oct 12, 2012·Diabetologia·K A M Jandeleit-Dahm, S P Gray
Sep 27, 2012·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Selim AyhanMehmet Yazici
Jul 8, 2008·Reviews in Endocrine & Metabolic Disorders·Ramachandran Ambady, Snehalatha Chamukuttan
Mar 6, 2010·Reviews in Endocrine & Metabolic Disorders·Matteo AnselminoLars Rydén
Aug 13, 2003·Current Atherosclerosis Reports·Gerald M Reaven
Jan 1, 1983·Preventive Medicine·G Rose
Jul 1, 1995·Diabetes Research and Clinical Practice·M SekiyaT Kamada
Aug 1, 1996·Diabetes Research and Clinical Practice·Q QiaoS L Kivelä

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.