PMID: 2033177Jun 1, 1991Paper

Coronary hemodynamics and myocardial metabolism in patients with syndrome X: response to pacing stress

Journal of the American College of Cardiology
P G CamiciM Marzilli

Abstract

Coronary hemodynamics, myocardial metabolism and left ventricular function at rest and after incremental atrial pacing were evaluated in 12 patients with stress-induced angina and ST segment depression, angiographically normal coronary arteries and no evidence of spasm, generally labeled as syndrome X, and in 10 normal subjects. At baseline study, great cardiac vein flow was comparable in patients and control subjects. During pacing, an equivalent rate-pressure product was reached in the two groups, but the slope of the relation between rate-pressure product and great cardiac vein flow was significantly less steep in patients than in normal subjects (0.0027 vs. 0.0054 ml/mm Hg.beat, p less than 0.001). Nevertheless, the left ventricular ejection fraction was comparable in both groups at rest (66 +/- 6% vs. 71 +/- 7%, p = NS) and during pacing (71 +/- 7% vs. 66 +/- 5%, p = NS). At baseline study, myocardial glucose extraction was more efficient in patients with syndrome X (p less than 0.05), but net myocardial exchange of pyruvate and alanine was, respectively, smaller and greater than in control subjects. Lactate was extracted to a similar extent in the two groups and in no instance was net lactate release observed during pacin...Continue Reading

References

Nov 1, 1976·The Journal of Clinical Investigation·G H MudgeM Lesch
Feb 1, 1989·The American Journal of Cardiology·R BugiardiniP Puddu
Aug 1, 1988·The American Journal of Cardiology·F RomeoA Reale
Mar 1, 1988·Metabolism: Clinical and Experimental·E Ferrannini
Jun 1, 1988·The American Journal of Cardiology·R O Cannon, S E Epstein
Aug 1, 1982·The American Journal of Cardiology·J A WisneskiJ P Beaudry

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Citations

Jan 1, 1993·Clinical Cardiology·C R Conti
Apr 1, 1997·Clinical Cardiology·C MammanaJ C Kaski
Apr 1, 1994·Cardiovascular Drugs and Therapy·P G CamiciA L'Abbate
Dec 7, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Patrick T SiegristPhilipp A Kaufmann
Jun 1, 1991·Journal of the American College of Cardiology·A Maseri
Nov 15, 1993·Journal of the American College of Cardiology·D TousoulisA Maseri
Mar 15, 1995·Journal of the American College of Cardiology·J C KaskiP A Poole-Wilson
May 1, 1995·Journal of the American College of Cardiology·J G WiedermannM Apfelbaum
Aug 1, 1994·Journal of the American College of Cardiology·A ChauhanP M Schofield
May 1, 1995·Journal of the American College of Cardiology·M A Alpert
Jun 9, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Robert A deKempRob S B Beanlands
Apr 1, 1997·The American Journal of Cardiology·F FontanaR Bugiardini
Jul 30, 1999·The American Journal of Cardiology·B E ErikssonC Sylvén
Nov 24, 1999·The American Journal of Cardiology·G A LanzaA Maseri
Nov 2, 1995·The American Journal of Cardiology·J C Kaski, P M Elliott
Oct 31, 2000·International Journal of Cardiology·J W ChenM S Chang
May 4, 2001·International Journal of Cardiology·B YaymaciI Dindar
Nov 15, 1996·Journal of the American College of Cardiology·G M RosanoP A Poole-Wilson
Jan 13, 1998·Journal of the American College of Cardiology·V PasceriA Maseri
Jun 17, 1998·Journal of the American College of Cardiology·D E NewbyD J Webb
Mar 26, 1999·Journal of the American College of Cardiology·H E BøtkerF Andreasen
Jun 21, 2002·The New England Journal of Medicine·Jonathan R PantingDudley J Pennell
Feb 23, 2007·The New England Journal of Medicine·Paolo G Camici, Filippo Crea
Aug 24, 2005·International Journal of Clinical Practice·E A Asbury, P Collins
Jun 1, 1995·Postgraduate Medical Journal·A Chauhan
Jan 2, 2010·American Journal of Physiology. Heart and Circulatory Physiology·Léna BorbouseJohnathan D Tune
Feb 2, 2010·American Journal of Physiology. Heart and Circulatory Physiology·Léna BorbouseJohnathan D Tune
Oct 23, 1997·The Journal of Clinical Investigation·H E BotkerT T Nielsen
Mar 3, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Satake OsamichiTakekoshi Noboru
Jul 27, 1999·Japanese Heart Journal·M Mohri, A Takeshita
Jun 6, 2002·British Journal of Clinical Pharmacology·David E Newby, Keith A A Fox

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