PMID: 15384013Sep 24, 2004Paper

Coronary revascularization in patients with renal insufficiency: restenosis rate and cardiovascular outcomes

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Tobias PinkauAlbert Schömig

Abstract

Several interventional trials have shown a lower success rate for coronary angioplasty and lower long-term event-free survival in patients with renal insufficiency, and data are conflicting about restenosis after coronary angioplasty. This study included 4,131 consecutive patients with coronary artery disease treated with coronary angioplasty (23%) or stenting (77%). Renal insufficiency is defined as a creatinine clearance (CrCl) less than 60 mL/min (<1.0 mL/s). Of 4,131 patients, 1,412 patients (34.2%) had renal insufficiency and 2,719 patients (65.8%) did not have renal insufficiency. The primary end point of the study is clinical restenosis, defined as the need for target-lesion revascularization. There was no difference in clinical restenosis rates between groups after 1 year (18.8% versus 18.4%; P = 0.75). The incidence of angiographic restenosis at the 6-month angiography was 32.7% in the group with renal insufficiency and 29.7% in the group without renal insufficiency ( P = 0.10). The composite end point of death and myocardial infarction was observed more frequently in patients with than without renal insufficiency (8.3% versus 3.2%; P < 0.001). Renal insufficiency was not independently associated with clinical restenos...Continue Reading

Citations

Mar 19, 2015·The American Journal of the Medical Sciences·Chong-Hui WangHong-Zhi Xie
Jul 14, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Melchior SeyfarthAlbert Schömig
Dec 7, 2007·International Journal of Cardiology·Turgay CelikErsoy Isik
Sep 4, 2015·Disease-a-month : DM·Richard GargiuloEdgar Lerma
Sep 8, 2005·The Annals of Pharmacotherapy·A Scott Mathis, James J Gugger
Apr 26, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Naofumi IkedaHiromichi Suzuki
Mar 1, 2008·Der Internist·J MannE L Schiffrin

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