Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution.

SAGE Open Medical Case Reports
Salman AlasfourYousif A Shamsaldeen

Abstract

Bartter syndrome is a rare autosomal recessive disorder characterized by hypokalaemia. Hypokalaemia is defined as low serum potassium concentration ˂3.5 mmol/L, which may lead to arrhythmia and death if left untreated. The aim of this case report was to normalize serum potassium concentration without the need for intravenous intervention. A 5-month-old male of 2.7 kg body weight diagnosed with Bartter syndrome was admitted to the general paediatric ward with acute severe hypokalaemia and urinary tract infection. The main challenge was the inability to administer drugs through intravenous route due to compromised body size. Therefore, we shifted the route of administration to the nasogastric tube/oral route. A total of 2 mL of concentrated intravenous potassium chloride (4 mEq potassium) were dissolved in distilled water and administered through nasogastric tube. Serum potassium concentration was rapidly normalized, which culminated in patient discharge. In conclusion, shifting drug administration from intravenous to oral route in a paediatric patient with Bartter syndrome includes numerous advantages such as patient convenience, minimized risk of cannula-induced infection, and reduced nurse workload.

References

Dec 1, 1990·Critical Care Medicine·G R PesolaG C Carlon
Jun 1, 1997·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·G MadrigalL M Guay-Woodford
Aug 15, 2003·The New England Journal of Medicine·Harry R Büller, Martin H Prins
May 10, 2006·Archives of Internal Medicine·Peter J KaboliJeffrey L Schnipper
Apr 30, 2009·The Journal of Antimicrobial Chemotherapy·Dominik MertzStefano Bassetti
May 7, 2014·Journal of Pharmacology & Pharmacotherapeutics·Jissa Maria Cyriac, Emmanuel James
Mar 16, 2018·Endocrine Connections·Efstratios KardalasAndromachi Vryonidou
Dec 7, 2018·International Journal of Nephrology and Renovascular Disease·Tamara da Silva Cunha, Ita Pfeferman Heilberg
Jul 30, 2020·The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology·Yeon Ji KimJin Mo Yang

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