PMID: 1195447Nov 1, 1975Paper

Correction by hyaluronidase of the interstitial tissue transport defect during shock: a new approach to therapy

The Journal of Trauma
I H KovenA Zhuk

Abstract

We have demonstrated a defect in tissue perfusion during hemorrhagic shock in dogs that is due in part to poor capillary flow, and in part to a defect in interstitial tissue diffusion. Treatment with whole blood alone improves capillary flow but diffusion remains defective. The use of hyaluronidase appears to correct the interstitial diffusion defect observed during shock.

Citations

Jan 1, 1996·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·S E Zimmet
Jan 1, 1984·The American Journal of Emergency Medicine·H Haljamäe
Dec 1, 1989·Medical Hypotheses·S W Bok

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