PMID: 8971967Dec 1, 1996Paper

Correction for scatter in 3D brain PET using a dual energy window method

Physics in Medicine and Biology
S GrootoonkT Jones

Abstract

A method for scatter correction using dual energy window acquisition has been developed and implemented on data collected with a brain-PET tomograph operated in the septa retracted, 3D mode. Coincidence events are assigned to (i) an upper energy window where both photons deposit energy between 380 keV and 850 keV or (ii) a lower energy window where one or both photons deposit within 200 keV and 380 keV. Scaling parameters are derived from measurements of the ratios of counts from line sources due to scattered and unscattered events in the two energy windows in head-sized phantoms. A scaled subtraction of the two energy windows produces a distribution of scatter which is smoothed prior to subtraction from the upper energy window. In phantoms, the correction was found to restore the uniformity, contrast and linearity of activity concentration. Relative activity concentrations were restored to within 7% of their true values in a multicompartment phantom. The method was found to provide accurate correction for scattered events arising from activity outside the direct detector field of view. In a three-compartment phantom containing water, 18F and 11C scanned in dynamic, multiframe mode, the half-lives of the two isotopes were resto...Continue Reading

References

Aug 1, 1992·Physics in Medicine and Biology·T J SpinksJ Reed
Jul 1, 1991·Physics in Medicine and Biology·M DefriseT Jones
Nov 1, 1994·Journal of Computer Assisted Tomography·V SossiT J Ruth
Jan 1, 1996·Physics in Medicine and Biology·J M Ollinger
Mar 1, 1994·Physics in Medicine and Biology·D L Bailey, S R Meikle
Jan 1, 1994·IEEE Transactions on Medical Imaging·M J Lercher, K Wienhard
Jan 1, 1991·IEEE Transactions on Medical Imaging·D W TownsendT Jones

❮ Previous
Next ❯

Citations

Feb 14, 1998·Annals of Nuclear Medicine·T FujiwaraS Takahashi
Aug 1, 1992·Annals of Nuclear Medicine·D L Bailey
Feb 28, 2013·Journal of Pharmacokinetics and Pharmacodynamics·Giampaolo Tomasi, Eric O Aboagye
Dec 7, 2002·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Ralph Myers, Susan Hume
Feb 24, 2001·Nuclear Medicine Communications·J S FlemingT D Fryer
Oct 19, 2001·Nuclear Medicine Communications·H Zaidi
Mar 15, 2006·Medical Physics·Lutz Frank SchelperManfred Baehre
May 9, 2012·Medical Physics·Spencer L BowenRamsey D Badawi
Sep 11, 2012·Medical Physics·L MolinerJ M Benlloch
Feb 9, 2002·Human Brain Mapping·Alexander HammersJohn Duncan
Aug 29, 2012·Zeitschrift für medizinische Physik·Axel Martinez-Möller, Stephan G Nekolla
May 27, 2009·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·M'hamed Bentourkia, Otman Sarrhini
Jan 1, 2008·PET Clinics·Adriaan A LammertsmaOtto S Hoekstra
Sep 21, 2004·IEEE Transactions on Medical Imaging·Jinyi Qi, Ronald H Huesman
Dec 2, 2010·IEEE Transactions on Medical Imaging·Bastien Guérin, Georges El Fakhri
Oct 6, 2000·IEEE Transactions on Medical Imaging·L E AdamR Freifelder
May 23, 2012·Computer Methods and Programs in Biomedicine·Otman Sarrhini, M'hamed Bentourkia
Oct 24, 2007·BMC Nuclear Medicine·Karin KnešaurekJong Ho Kim
Aug 19, 2016·Annals of Nuclear Medicine·Masanobu IbarakiToshibumi Kinoshita
Feb 16, 2005·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Karin Knesaurek, Josef Machac
Jul 25, 2017·Physics in Medicine and Biology·Ahmadreza RezaeiJohan Nuyts
Aug 31, 2002·Physics in Medicine and Biology·Jinyi Qi, Ronald H Huesman
May 26, 2006·Physics in Medicine and Biology·Lucreţiu M PopescuJoel S Karp
Jul 25, 2006·Physics in Medicine and Biology·Jinyi Qi, Richard M Leahy
May 6, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Eugenii A RabinerPaul M Grasby
Oct 6, 2005·Physics in Medicine and Biology·Arman RahmimVesna Sossi
Jul 28, 2017·Physics in Medicine and Biology·Hamidreza HemmatiPardis Ghafarian
May 24, 2003·Brain : a Journal of Neurology·Alexander HammersJohn S Duncan
Mar 11, 2011·Physics in Medicine and Biology·S Naidoo-VariawaS R Meikle
Oct 26, 2000·Physics in Medicine and Biology·E TanakaH Murayama
Oct 2, 1998·Physics in Medicine and Biology·V SossiT J Ruth
Sep 29, 2000·Physics in Medicine and Biology·T J SpinksR Nutt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.