PMID: 2479993Jan 1, 1989Paper

[Correction of disorders of systemic hemodynamics and rheologic indices of the blood in patients with chronic kidney failure during hemodialysis].

Terapevticheskiĭ arkhiv
L E VlasovS I Slizskiĭ

Abstract

During hemodialysis, 44 patients with terminal chronic renal failure were examined for the systemic hemodynamics and blood rheological properties as well as for the possibility of their correction by infusion of the plasma substitutes: polyglucine, rondex or 10% albumin at a volume of 400 ml per administration. It was established that patients on hemodialysis manifested pronounced hemodynamic and rheological disorders. During hemodialysis, the hemodynamic disorders correlated with the changes in the rheological properties of the blood (r = 0.23-0.45, p less than 0.05). It is indicated that to treat the hypotensive states occurring in the course of hemodialysis, infusions of the plasma expanders, rondex, 10% albumin and polyglucine may be used at a limited volume. The plasma substitute rondex ensures a more favorable hemodynamic and rheological effect, comparing very favourably with other preparations investigated.

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