PMID: 1210118Jan 1, 1975Paper

Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin

Voprosy onkologii
V M Dil'manI G Kovaleva

Abstract

The study was conducted on 40 patients previously operated upon radically for cancer of the mammary gland, uterine body, lung and colon. All patients were explored and treated during 2-14 months. As evidenced by the data obtained, biguanides proved to be mostly effective with regard to normalization of an excessive weight in oncological patients and an impared tolerance to glucose, whereas myscleron-in cases of hyperlipemia with marked hypercholesterinemia, diphenin - in a concomitant excessive production of corticosteroids. Moreover, the pharmacological drugs concerned were shown to influence also the production of gonadotropic, steroid and thyroid hormones.

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