Correction of oral contrast artifacts in CT-based attenuation correction of PET images using an automated segmentation algorithm.

European Journal of Nuclear Medicine and Molecular Imaging
Alireza AhmadianH Zaidi

Abstract

Oral contrast is usually administered in most X-ray computed tomography (CT) examinations of the abdomen and the pelvis as it allows more accurate identification of the bowel and facilitates the interpretation of abdominal and pelvic CT studies. However, the misclassification of contrast medium with high-density bone in CT-based attenuation correction (CTAC) is known to generate artifacts in the attenuation map (mumap), thus resulting in overcorrection for attenuation of positron emission tomography (PET) images. In this study, we developed an automated algorithm for segmentation and classification of regions containing oral contrast medium to correct for artifacts in CT-attenuation-corrected PET images using the segmented contrast correction (SCC) algorithm. The proposed algorithm consists of two steps: first, high CT number object segmentation using combined region- and boundary-based segmentation and second, object classification to bone and contrast agent using a knowledge-based nonlinear fuzzy classifier. Thereafter, the CT numbers of pixels belonging to the region classified as contrast medium are substituted with their equivalent effective bone CT numbers using the SCC algorithm. The generated CT images are then down-sam...Continue Reading

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Citations

Aug 16, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Ronald BoellaardJan Pruim
Aug 23, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Margit KleisBenjamin L Franc
Sep 13, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Doumit Daou
Apr 14, 2010·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Mohammad R AyHabib Zaidi
Dec 7, 2013·Theranostics·Bing BaiPeter S Conti
Apr 10, 2012·Medical Physics·B TeimourianH Zaidi
Dec 8, 2009·Magnetic Resonance Imaging Clinics of North America·Habib ZaidiAbass Alavi
Jul 1, 2008·PET Clinics·Habib ZaidiAbass Alavi
Mar 1, 2018·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Charles M LaymonJames M Mountz
May 10, 2021·Seminars in Nuclear Medicine·Vetri Sudar JayaprakasamHeiko Schöder

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