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Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease

Journal of Alzheimer's Disease : JAD

Feb 18, 2020

Eleonora CipollariAlzheimer’s Disease Metabolomics Consortium

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PubMed

Abstract

Basic research has implicated intracellular cholesterol in neurons, microglia, and astrocytes in the pathogenesis of Alzheimer's disease (AD), but there is presently no assay to access intracellular cholesterol in neural cells in living people in the context of AD. To devise and charact...read more

Mentioned in this Paper

Cohort
Neuroblastoma
High Density Lipoprotein Measurement
Lines protein, Drosophila
Neurons
Alzheimer's Disease
Screening Generic
Biological Markers
Source
Cholesterol Efflux
1
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Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease

Journal of Alzheimer's Disease : JAD

Feb 18, 2020

Eleonora CipollariAlzheimer’s Disease Metabolomics Consortium

PMID: 32065798

DOI: 10.3233/jad-191246

Abstract

Basic research has implicated intracellular cholesterol in neurons, microglia, and astrocytes in the pathogenesis of Alzheimer's disease (AD), but there is presently no assay to access intracellular cholesterol in neural cells in living people in the context of AD. To devise and charact...read more

Mentioned in this Paper

Cohort
Neuroblastoma
High Density Lipoprotein Measurement
Lines protein, Drosophila
Neurons
Alzheimer's Disease
Screening Generic
Biological Markers
Source
Cholesterol Efflux
1

Feeds With Similar Papers

Cerebrovasculature & ApoE

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Alzheimer's Disease: Tau & TDP-43

Alzheimer's disease is a chronic neurodegenerative disease. This feed focuses on the underlying role of Tau proteins and TAR DNA-binding protein 43, as well as other genetic factors, in Alzheimer's.

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