Correlates of bone mineral density in elderly patients with hip fractures

Journal of Orthopaedic Trauma
D R DirschlW S Oakley

Abstract

Ninety-seven elderly patients with acute fractures of the proximal femur sustained as a result of minimal trauma were studied with regard to variables that may potentially influence the incidence or outcome of fractures of the proximal femur. The mean bone mineral density (BMD) measured at the femoral neck was approximately 2 SDs below age- and sex-adjusted normals. There was a preferential loss of bone mineral from the femoral neck in younger patients with hip fractures (Z score -3.10 +/- 0.23) (mean +/- SEM) compared with the lumbar spine (Z score -1.71 +/- 0.41). Mean daily calcium intake was well below the recommended levels and calcium intake < 400 mg/day was associated with lower lumbar spine BMD Z scores (p = 0.01). Ambulatory ability was unassociated with BMD Z scores. The results of this study suggest that the femoral neck is a site of preferential bone loss in younger postmenopausal patients, and screening of patients at risk of hip fracture should measure BMD at this site. Calcium supplementation may play a role in decreasing the incidence of hip fractures.

Citations

Mar 4, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·M T ParviainenE Alhava
Dec 9, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H OkuizumiN Konishi
May 20, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jay S MagazinerCarl F Pieper
Feb 6, 2020·The Bone & Joint Journal·Jason S HoellwarthMunjed Al Muderis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.