PMID: 3749512Jan 1, 1986Paper

Correlates of increased risk for alcoholism in young men

Progress in Neuro-psychopharmacology & Biological Psychiatry
S O'ConnorA Tasman

Abstract

Healthy men, aged 21-28, were divided into two groups according to the DSM-III diagnosis of alcoholism in their biological fathers. Evoked potentials from each subject were measured according to a visual odd-ball paradigm designed to elicit large responses in the midline parietal, Pz, lead. Subjects with alcoholic fathers produced significantly smaller amplitudes of the P3 component compared to subjects with non-alcoholic fathers. Reaction time, task difficulty and subject drinking history did not distinguish the groups. Subject's drinking history was not related to P3 amplitude.

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