Abstract
The purpose of this cross-sectional study was to describe the relationship between low density lipoprotein cholesterol (LDL-C) and various physical, chemical, dietary, and behavioral attributes of 4768 white men and women aged 20-59 years from 10 North American populations sampled by the Lipid Research Clinics Program. For our analyses, women were separated into two groups: users and nonusers of hormones. A positive correlation coefficient between very low density lipoprotein cholesterol (VLDL-C) and LDL-C was observed for women but not for men. Fasting plasma concentrations of LDL-C were most strongly and consistently associated in each gender with age, the Quetelet Index of body mass, the number of cigarettes smoked per day, systolic blood pressure, and the levels of plasma glucose and uric acid (all positive associations); and with height and bilirubin levels (both negative associations). Gender-related differences were found in the associations between LDL-C and the other lipids and lipoprotein cholesterol fractions measured. The associations between LDL-C and individual nutrients computed from a 24-hour dietary recall were generally of a low-order magnitude. The strongest and most consistent among the statistically signifi...Continue Reading
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