Correlating gamma-aminobutyric acidergic circuits and sensory function in the electrosensory lateral line lobe of a gymnotiform fish

The Journal of Comparative Neurology
L Maler, E Mugnaini

Abstract

Electric fish generate an electric field, which they sense with cutaneous electroreceptors. Electroreceptors project topographically onto the medullary electrosensory lateral line lobe (ELL). The ELL of gymnotiform electric fish is divided into four segments specialized to detect different aspects of the electrosensory input; it is also laminated with separate laminae devoted to electroreceptive input, interneurons, projection neurons, and feedback input. We have utilized antisera to glutamic acid decarboxylase (GAD) and gamma-aminobutyric acid (GABA) to map the distribution of GABAergic cells and fibers in the ELL of the gymnotiform fish, Apteronotus leptorhynchus. Six types of GABAergic interneurons are found in ELL: Type 2 granular cells (granular layer) project to pyramidal cells; polymorphic cells (pyramidal cell layer) project to the non-GABAergic type 1 granular cells; ovoid cells (deep neuropil layer) project bilaterally upon basilar dendrites of pyramidal cells; multipolar cells (deep neuropil layer) project bilaterally, probably to dendrites and neurons within the deep neuropil layer; and neurons of the ventral molecular layer and stellate cells (molecular layer) project to apical dendrites of pyramidal cells. GABAerg...Continue Reading

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Citations

May 20, 1999·The Journal of Comparative Neurology·L Maler, M T Hincke
Dec 18, 2001·The Journal of Comparative Neurology·A J RashidR W Turner
Jan 21, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·W H MehaffeyR W Turner
Dec 25, 2003·Journal of Physiology, Paris·Sheryl CoombsMark Nelson
May 30, 2008·Journal of Neurophysiology·Rüdiger KraheMaurice J Chacron
Sep 20, 2006·Proceedings of the National Academy of Sciences of the United States of America·Jason W MiddletonLeonard Maler
Jun 17, 1998·Proceedings of the National Academy of Sciences of the United States of America·D Wang, L Maler
Aug 5, 2014·Journal of Physiology, Paris·Ana Carolina PereiraAngel A Caputi
Nov 6, 2008·Journal of Physiology, Paris·W Hamish MehaffeyRay W Turner
Aug 23, 2012·The Journal of Comparative Neurology·Brenda Toscano-MárquezRüdiger Krahe
Oct 11, 2007·Progress in Brain Research·Leonard Maler
Dec 9, 2003·Nature Reviews. Neuroscience·Rüdiger Krahe, Fabrizio Gabbiani
Jan 20, 2019·The Journal of Experimental Biology·Angel Ariel Caputi, Pedro Aníbal Aguilera
Feb 9, 2007·Journal of Neurophysiology·Daniel GussinLeonard Maler
Mar 28, 2008·Journal of Neurophysiology·W Hamish MehaffeyRay W Turner
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Sep 21, 2013·Journal of Neurophysiology·Erik Harvey-Girard, Leonard Maler
Oct 5, 2002·Journal of Neurophysiology·John E Lewis, Leonard Maler
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Nov 13, 2015·Journal of Neurophysiology·Curtis M MarcouxLeonard Maler
Jan 12, 2001·Journal of Neurophysiology·J Bastian, J Nguyenkim

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