Correlating imaging and histopathology of an odontogenic keratocyst in the nevoid basal cell carcinoma syndrome

Dento Maxillo Facial Radiology
L Janse van RensburgI Thompson

Abstract

We present the correlative diagnostic imaging and histological findings in a case of multiple odontogenic keratocysts (OKC) associated with the Nevoid Basal Cell Carcinoma Syndrome (NBCC). Whilst CT displayed aspects of bone morphology not visible on the plain films, contrast-enhanced MR provided the essential macropathological detail, including focal wall-enhancement and iso-intense intraluminal soft-tissue masses which correlated with the histological findings of focal inflammatory ulceration of the cyst lining, orthokeratosis and cell debris. The features identified by these combined imaging techniques are helpful in distinguishing the OKC from other cysts or neoplastic lesions and can therefore alter surgical management.

References

Mar 1, 1992·Irish Journal of Medical Science
Jan 1, 1996·AJR. American Journal of Roentgenology·R J Zagoria, A D Elster

❮ Previous
Next ❯

Citations

Aug 25, 2012·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Virginia E KimonisSherri J Bale
Jan 25, 2005·Dento Maxillo Facial Radiology·O Ferreira JúniorJ R P Lauris
Mar 3, 1998·Dento Maxillo Facial Radiology·J H ErasmusA J van der Westhuijzen
Feb 23, 2010·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Aditya BharathaEugene Yu
May 26, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Ieda Crusoé-RebelloJean Nunes dos Santos
May 13, 2015·Clinical Imaging·Mohamed MetkeesAshok Srinivasan
Jun 30, 2012·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Fadi TitinchiLeon Janse van Rensburg
Nov 25, 2003·Neuroimaging Clinics of North America·Kazunori YoshiuraSteven J Scrivani
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Leon Janse van RensburgChristoffel J Nortjé
Jun 26, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Fadi Titinchi, Christoffel J Nortje

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.