Correlation and comparison of magnetic and electric detection of small intestinal electrical activity

The American Journal of Physiology
L Alan BradshawWilliam O Richards

Abstract

The small intestinal basic electrical rhythm (BER) was detected simultaneously with serosal electrodes and a transabdominal superconducting quantum interference device (SQUID) magnetometer in anesthetized rabbits. We induced mesenteric ischemia to correlate serosal electrode recording of changes in BER with the SQUID magnetometer. The BER frequency was obtained by spectral analysis of the data using Fourier and autoregressive techniques. There was a high degree of correlation (r = 0.96) between the BER frequency determined using the serosal electrodes and the BER frequency ascertained from SQUID data. Additionally, the effects of an electrical insulator on the external electric and magnetic fields were studied in the rabbit model. The presence of an insulator profoundly attenuates external electric potentials recorded by cutaneous electrodes but does not significantly affect external magnetic fields or serosal potentials. We conclude that SQUID magnetometers could noninvasively record small intestinal BER that was highly correlated with the activity recorded by invasive serosal electrodes. The advantages of magnetic field measurements have encouraged us to investigate clinical applications.

Citations

Nov 29, 2005·Physiological Measurement·Andrei Irimia, L Alan Bradshaw
Jul 29, 2009·Physiological Measurement·Y Ye-LinJ L Martinez-de-Juan
Jan 15, 2010·Physics in Medicine and Biology·Y Ye-LinJ L Ponce
Mar 17, 2010·Annals of Biomedical Engineering·Y Ye-LinJ L Martinez-de-Juan
May 31, 2007·Medical & Biological Engineering & Computing·Y YeJ L Ponce
Sep 9, 2005·Physics in Medicine and Biology·Andrei Irimia, L Alan Bradshaw
Dec 20, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Michael HockeAndreas Stallmach

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