Correlation between BMI and PASI in patients affected by moderate to severe psoriasis undergoing biological therapy

Dermatologic Therapy
F BardazziA Patrizi

Abstract

Obesity is common in psoriatic patients, and it has been shown to be important for many aspects of the condition. In particular, low-calorie diets can improve the symptoms and response to treatment in pustular psoriasis. The present study investigates the influence of body-weight alteration on the disease's clinical manifestations in moderate to severe psoriasis patients treated with biological drugs. Finally, the influence of a caloric restriction was assessed. This observational transversal study enrolled 33 patients attending our Severe Psoriasis Outpatient Clinic, who were treated with biological drugs. Body Mass Index (BMI) was used as a diagnostic indicator of being overweight and of obesity. Waist circumference was also measured. Body weight and Psoriasis Area Severity Index (PASI) index were measured at follow-up visits at 4 and 8 months. Nonparametric test of Mann-Whitney was used to detect the differences between patient groups. Fisher's exact test was performed to evaluate the different results depending on the therapeutic changes of BMI. There was a strong prevalence of overweight-obese individuals in the group with a mean BMI of 30.59 +/- 6.94. Waist circumference was also above normal in the majority of the patien...Continue Reading

References

Aug 10, 2002·American Journal of Physiology. Endocrinology and Metabolism·Gladys YumetRobert N Cooney
Nov 27, 2002·Journal of the American Academy of Dermatology·Gerald G KruegerUNKNOWN Alefacept Clinical Study Group
Dec 21, 2005·Archives of Dermatology·Mark D HerronGerald G Krueger
Jul 14, 2007·The British Journal of Dermatology·W SterryUNKNOWN International Psoriasis Council
Sep 24, 2008·Dermatology : International Journal for Clinical and Investigative Dermatology·Luigi NaldiRosanna Cuscito

❮ Previous
Next ❯

Citations

Mar 27, 2013·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·K Lau, P H Höger
Aug 29, 2013·Clinical Drug Investigation·Susana CoimbraAlice Santos-Silva
Jan 26, 2016·Autoimmunity Reviews·Florenzo IannoneGiovanni Lapadula
Oct 29, 2013·Clinics in Dermatology·Nikita LakdawalaJane M Grant-Kels
Jan 10, 2012·Diabetes & Metabolism·M BuysschaertV Preumont
Aug 8, 2013·The Journal of Investigative Dermatology·Emily Edson-HerediaTomoko Maeda-Chubachi
Jul 23, 2013·International Journal of Dermatology·Anne-Marie TobinBrian Kirby
Nov 9, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·E DaudénUNKNOWN Working Group on Comorbidity in Psoriasis
May 14, 2011·The British Journal of Dermatology·A R Shipman, G W M Millington
Jun 14, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·T AhernD O'Shea
Jun 16, 2010·The British Journal of Dermatology·G BandoliC D Chambers
Jul 24, 2014·Dermatologic Therapy·Jacek KarczewskiZygmunt Adamski
Jan 3, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·V A AntonucciF Bardazzi
Dec 3, 2014·Journal of the American Academy of Dermatology·Era Caterina MurzakuBabar K Rao
Apr 9, 2014·Journal of the American Academy of Dermatology·Maya DebbanehWilson Liao
May 24, 2011·Actas dermo-sifiliográficas·M M FaríasC de la Cruz
Mar 27, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·M GiannoniA Offidani
Apr 30, 2015·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S Upala, A Sanguankeo
Sep 21, 2012·Scandinavian Journal of Rheumatology·F IannoneG Lapadula
Oct 25, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·S CoimbraA Santos-Silva
Jul 28, 2016·International Journal of Environmental Research and Public Health·Luigi BarreaSilvia Savastano
Mar 30, 2017·The Journal of Dermatology·Jinrong ZengQianjin Lu
Aug 15, 2015·Journal of Cutaneous Medicine and Surgery·Patrick FlemingCharles Lynde
Dec 8, 2017·Dermatologic Therapy·Giulia Odorici, Andrea Conti
Sep 25, 2020·Critical Reviews in Food Science and Nutrition·Luigi BarreaGiovanna Muscogiuri
Sep 8, 2019·International Journal of Molecular Sciences·Koji KamiyaMamitaro Ohtsuki
Jun 27, 2020·Mediators of Inflammation·Anna Michalak-StomaGrażyna Chodorowska
Jul 6, 2019·Mediators of Inflammation·Carmen Rodríguez-CerdeiraJosé Luís González-Cespón
Feb 6, 2020·Clinical Rheumatology·Luca MoroniLorenzo Dagna
Aug 6, 2020·International Journal of Molecular Sciences·Naoko KandaHidehisa Saeki
Jan 30, 2021·The Journal of Dermatology·Virginia ValentiniAntonio Giovanni Richetta
Aug 11, 2021·Pharmaceutics·Jen-Chih TsengTsung-Hsien Chuang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the American Academy of Dermatology
Alexa B KimballNational Psoriasis Foundation
Journal of the American Academy of Dermatology
T Henseler, E Christophers
JAMA : the Journal of the American Medical Association
Joel M GelfandAndrea B Troxel
Journal of the American Academy of Dermatology
Lily Clark, Mark Lebwohl
© 2021 Meta ULC. All rights reserved