Correlation between clinical characteristics and chest computed tomography findings of pulmonary cryptococcosis

Pulmonary Medicine
Hideaki YamakawaKazuyoshi Kuwano

Abstract

The aim of this study was to review HIV-negative patients with pulmonary cryptococcosis to analyze the correlations between clinical characteristics and chest computed tomography (CT) findings. We retrospectively analyzed medical records of 16 HIV-negative patients with pulmonary cryptococcosis diagnosed at our institution, and clinical characteristics of the patients with nodules or masses without ground-glass attenuation (GGA)/consolidation type were compared with those of patients with inclusive GGA or consolidation type. Host status was immunocompromised (81.2%) in most of the patients, and 6 (37.5%) were asymptomatic. The most frequent radiologic abnormalities on chest CT scans were one or more nodules (87.5%), GGA (37.5%), and consolidations (18.8%). Most lesions were located in the lower lung. Levels of hemoglobin and platelets were significantly lower in patients with inclusive GGA or consolidation type. Although the differences were not significant, patients with inclusive GGA or consolidation type tended to have a C-reactive protein level of ≥1.0 mg/dL. If a patient with anemia and thrombocytopenia shows GGA or consolidation in the lung, pulmonary cryptococcosis should be given careful consideration.

References

Mar 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R Rozenbaum, A J Gonçalves
Jan 1, 1994·Journal of Thoracic Imaging·L Sider, M A Westcott
Jun 8, 2001·Trends in Microbiology·M FeldmesserA Casadevall
Dec 11, 2003·Chest·Hassan F NadrousJay H Ryu
Jun 5, 2004·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·Kazuma KishiKunihiko Yoshimura
Jul 1, 2005·Radiology·Rebecca M LindellJay H Ryu
Oct 22, 2005·Respiratory Medicine·Kazuma KishiKunihiko Yoshimura
Aug 30, 2006·Scandinavian Journal of Infectious Diseases·Chih-Jen YangMing-Shyan Huang
Jan 31, 2009·Clinical and Investigative Medicine. Médecine Clinique Et Experimentale·Benquan WuTiantuo Zhang
Apr 9, 2009·Current Opinion in Pulmonary Medicine·Rhett M Shirley, John W Baddley
May 14, 2010·Proceedings of the American Thoracic Society·Shu Shun Li, Christopher H Mody
Nov 17, 2012·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Jin-Quan YuRichard W Light
Dec 22, 2012·Medical Mycology Journal·Keiko Ishii, Kazuyoshi Kawakami

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Citations

Apr 27, 2017·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Qingtao KongHong Sang
Jun 13, 2020·The Journal of International Medical Research·Huan-Huan WuShuang-Yan Fang
Dec 14, 2018·Experimental and Therapeutic Medicine·Dongxu WangXinying Xue
Feb 6, 2019·Case Reports in Radiology·Francisco Barbosa De Araujo NetoMárcio Valente Yamada Sawamura
Jun 18, 2021·Respiratory Medicine·D WilmesN Kanaan

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Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

SPSS

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