Correlation between coronary perfusion pressure and quantitative ECG waveform measures during resuscitation of prolonged ventricular fibrillation.

Resuscitation
Joshua C ReynoldsJames J Menegazzi

Abstract

The ventricular fibrillation (VF) waveform is dynamic and predicts defibrillation success. Quantitative waveform measures (QWMs) quantify these changes. Coronary perfusion pressure (CPP), a surrogate for myocardial perfusion, also predicts defibrillation success. The relationship between QWM and CPP has been preliminarily explored. We sought to further delineate this relationship in our porcine model and to determine if it is different between animals with/without ROSC (return of spontaneous circulation). A relationship exists between QWM and CPP that is different between animals with/without ROSC. Utilizing a prior experiment in our porcine model of prolonged out-of-hospital VF cardiac arrest, we calculated mean CPP, cumulative dose CPP, and percent recovery of three QWM during resuscitation before the first defibrillation: amplitude spectrum area (AMSA), median slope (MS), and logarithm of the absolute correlations (LAC). A random effects linear regression model with an interaction term CPP ROSC investigated the association between CPP and percent recovery QWM and how this relationship changes with/without ROSC. For 12 animals, CPP and QWM measures (except LAC) improved during resuscitation. A linear relationship existed betw...Continue Reading

References

Jan 1, 1985·The American Journal of Cardiology·J T NiemannJ M Criley
Jan 1, 1985·Annals of Internal Medicine·W D WeaverM K Copass
Mar 1, 1985·The American Journal of Emergency Medicine·D L CardenM C Tomlanovich
Jul 1, 1985·Journal of the American College of Cardiology·A B SandersG A Ewy
Mar 1, 1980·Critical Care Medicine·C F Babbs
Jul 1, 1996·Journal of the American College of Cardiology·K B KernR A Berg
Apr 13, 1999·JAMA : the Journal of the American Medical Association·L A CobbA P Hallstrom
May 13, 1999·Critical Care Medicine·M NocJ Bisera
Jan 22, 2002·Critical Care Medicine·A Marn-PernatJ Bisera
Apr 12, 2002·Resuscitation·Heitor P PovoasAnn Barbatsis
Dec 17, 2002·JAMA : the Journal of the American Medical Association·Myron L Weisfeldt, Lance B Becker
Mar 15, 2003·JAMA : the Journal of the American Medical Association·Lars WikPetter Andreas Steen
Mar 1, 1963·Anesthesiology·J S REDDING, J W PEARSON
May 1, 2007·Resuscitation·Joar EilevstjønnKjetil Sunde
Nov 15, 2008·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·David D SalcidoJon C Rittenberger
Dec 2, 2009·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Joshua C ReynoldsJames J Menegazzi

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Citations

Aug 1, 2015·Emergency Medicine Clinics of North America·Francis X GuyetteUNKNOWN Post Cardiac Arrest Service
Mar 21, 2019·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Allison C KollerJames J Menegazzi
Feb 21, 2021·Annals of the New York Academy of Sciences·Tom P AufderheideDemetris Yannopoulos

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