Correlation between flagellin A (flaA) genotypes and antimicrobial susceptibility patterns of Campylobacter jejuni strains isolated from children with gastroenteritis in Athens, Greece.

Molecular Diagnosis & Therapy
Anastassios IoannidisStylianos Chatzipanagiotou

Abstract

Campylobacter jejuni is one of the most common enteric pathogens worldwide. The bacterium is transmitted to humans via contaminated food and water. In the majority of cases the disease is self-limiting, but treatment is indicated in immunocompromised patents, in severe cases with septicemia, and in children. The subtyping of clinical, animal, and food C. jejuni isolates is very important for epidemiological studies. In the present study, 192 Campylobacter jejuni isolates characterized by pulsed-field gel electrophoresis (PFGE) of SmaI digested genomic DNA were further examined with respect to their antimicrobial resistance and their flagellin A (flaA) genotypes in order to disclose any correlation between a certain flaA type and a specific antimicrobial susceptibility pattern. C. jejuni clinical isolates were collected from infected children up to 14 years of age from five general hospitals in the area of Attica, Greece, during the period 2004-7. C. jejuni strain isolation and identification from stool samples were performed by conventional bacteriological methods. SmaI restriction fragments were prepared as described previously for the PFGE analysis. Antimicrobial susceptibility was tested and interpreted by determination of t...Continue Reading

References

Feb 1, 1995·The Journal of Antimicrobial Chemotherapy·J ReinaV Fernandez-Baca
Feb 1, 1996·Journal of Clinical Microbiology·I NachamkinC M Patton
Jan 5, 2000·Applied and Environmental Microbiology·T M Wassenaar, D G Newell
May 11, 2002·The Journal of Antimicrobial Chemotherapy·S ChatzipanagiotouN I Legakis
Nov 18, 2006·European Journal of Epidemiology·Anastassios IoannidisStylianos Chatzipanagiotou
Dec 13, 2006·Molecular Diagnosis & Therapy·Anastassios IoannidisStylianos Chatzipanagiotou
Feb 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anders TernhagKarl Ekdahl
Nov 1, 2008·BMC Infectious Diseases·Ji-Rong YangJung-Jung Mu
Jun 13, 2009·Methods in Molecular Biology·Tansy M Peters

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Citations

Nov 3, 2010·Foodborne Pathogens and Disease·Panagiota GousiaChrissanthy Papadopoulou

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