Correlation between metabolic syndrome and sleep apnea

World Journal of Diabetes
Alejandro CastanedaSalim Surani

Abstract

The so-called "metabolic syndrome" (MS), constitutes a cluster of metabolic and cardiovascular abnormalities, including fasting glucose, blood pressure, triglycerides, high density lipoprotein cholesterol (HDL-C), and waist circumference that arise from insulin resistance. Obstructive sleep apnea (OSA) syndrome is characterized by recurrent episodes of partial or complete obstruction of the upper airway, involving cessation or significant decreased airflow, with intermittent hypoxemia, frequent arousals from sleep and recurrent oxyhemoglobin desaturations that interfere with normal sleep patterns generating difficulty falling asleep, unrefreshing sleep and loud snoring. The relation between these two entities is known as "Syndrome Z", and there is no question about the impact of these risk factors on health and disease. This clinical condition presents a growing epidemic Worldwide, affecting approximately 60% of the general population with both MS and OSA due to the constant increase of body mass index in humans. This article presents evidence-based data that focuses on the direct relationship between MS and OSA.

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Citations

May 8, 2020·Metabolic Syndrome and Related Disorders·Kostas ArchontogeorgisPaschalis Steiropoulos
Dec 4, 2019·Journal of Medical Imaging and Radiation Oncology·Andy Whyte, Daren Gibson
Feb 14, 2020·International Angiology : a Journal of the International Union of Angiology·Bin XuLi-Ge Liu
Nov 18, 2019·Pathology, Research and Practice·Won Jin Cho, Jung-Soo Pyo
Apr 30, 2021·Frontiers in Cell and Developmental Biology·Vincenza FrisardiMaria Elisabeth Street
Jun 3, 2021·International Journal of Molecular Sciences·David Sanz-RubioDavid Gozal

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