Correlation between micturitional urethral pressure profile and pressure-flow criteria in bladder outlet obstruction

The Journal of Urology
C E DuBeauS V Yalla

Abstract

We correlate micturitional urethral pressure profilometry with pressure-flow diagnoses of outlet obstruction. Urodynamic evaluation was done of 86 consecutive men with voiding symptoms. Obstruction criteria were a micturitional urethral pressure profile (MUPP) gradient greater than 5 cm. water, Schäfer's linear passive urethral resistance relation (PURR) greater than grade 1 and Abrams-Griffiths nomogram. Interpretable results were completed in 99% of the patients undergoing MUPP and 60% undergoing pressure-flow studies (p < 0.00001). MUPP diagnosis agreed with PURR (p = 0.0015) and Abrams-Griffiths nomogram results (p = 0.00004). MUPP gradients correlated well with PURR (r = 0.70, p < 0.00001). Using optimum cutoff values (11 cm. water), the sensitivity of MUPP was 83%, specificity 82% and positive predictive value 94%. MUPP correlates well with and yields interpretable results more often than pressure-flow studies.

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Citations

Jun 27, 2002·Current Urology Reports·C E Kelly, R J Krane
May 1, 1996·The Urologic Clinics of North America·M P SullivanS V Yalla
Sep 15, 1998·Journal of the American Geriatrics Society·C E DuBeauN M Resnick
Apr 26, 2003·Der Urologe. Ausg. A·R BergesUNKNOWN DGU-Leitlinienkommission
May 23, 1998·The Journal of Urology·R Kirschner-HermannsN M Resnick

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