Correlation between Obstructive Sleep Apnea and Non-Alcoholic Fatty Liver Disease before and after Metabolic Bariatric Surgery.

Obesity Surgery
Y X ZhangB Wang

Abstract

Emerging evidence has revealed that obstructive sleep apnea (OSA) is associated with non-alcoholic fatty liver disease (NAFLD). However, the impact of OSA on NAFLD among obese patients undergoing metabolic and bariatric surgery (MBS), especially during follow-up period, remains unclear. To analyze the correlation based on preoperative characteristics and postoperative conditions among bariatric patients with comorbid OSA and NAFLD. Clinical data of patients who underwent MBS in our institution between January 2016 and June 2019 were reviewed retrospectively. Correlation analysis and linear regressions were used to identify how OSA links with NAFLD before and after treatment of MBS. Of 308 patients, 181 were diagnosed with OSA and enrolled in the present study, and 127 completed follow-up visits at 6 months. The proportion of NAFLD in the mild-moderate OSA and severe OSA groups was 75.0% and 96.0%, respectively. MBS was effective at improving sleep apnea and nocturnal hypoxia, as well as liver steatosis and fibrosis (P < 0.05). And we also found that there were significant correlations not only between OSA- and NAFLD-related characteristics at baseline but also between their improvements after surgery, eventually leading to simi...Continue Reading

References

Nov 21, 1998·Digestive Diseases and Sciences·M P HockingE R Woodward
May 26, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Florence TannéLawrence Serfaty
Mar 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Paul AnguloChristopher P Day
Mar 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Vladimir SavranskyVsevolod Y Polotsky
Aug 11, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·Vladimir SavranskyVsevolod Y Polotsky
Feb 6, 2008·Proceedings of the American Thoracic Society·Esra Tasali, Mary S M Ip
Apr 19, 2008·Journal of Digestive Diseases·Min De ZengUNKNOWN Chinese National Consensus Workshop on Nonalcoholic Fatty Liver Disease
Sep 29, 2011·Journal of Hepatology·Maud Lemoine, Lawrence Serfaty
Feb 8, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·G MussoR Gambino
Jun 19, 2013·Journal of the American College of Cardiology·Luciano F DragerGeraldo Lorenzi-Filho
Jul 24, 2013·Journal of Gastroenterology and Hepatology·Jian-Gao Fan
Apr 29, 2015·Gastroenterology·Guillaume LassaillyPhilippe Mathurin
Jan 30, 2016·Metabolism: Clinical and Experimental·Elena BuzzettiEmmanuel A Tsochatzis
Jul 28, 2016·Antioxidants & Redox Signaling·Schohraya SpahisEmile Levy
Jul 31, 2016·The Surgical Clinics of North America·Jesse Clanton, Michael Subichin
Jan 29, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Parambir S DulaiRohit Loomba
Apr 19, 2017·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Richard B BerryBradley V Vaughn
May 20, 2017·Metabolism: Clinical and Experimental·Michael DoulberisPanagiotis Katsinelos
May 30, 2017·The Journal of International Medical Research·Kosuke SakitaniKazuhiko Koike
Jul 4, 2017·Journal of Gastroenterology and Hepatology·Vincent Wai-Sun WongGeoff Farrell
Jul 18, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Naga ChalasaniArun J Sanyal
Aug 13, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Chris EstesArun J Sanyal
Jan 18, 2018·JAMA : the Journal of the American Medical Association·Gunn Signe JakobsenJøran Hjelmesæth
Apr 11, 2018·Gastroenterología y hepatología·Rocío AllerManuel Romero-Gómez
Aug 1, 2018·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Ali AminianUNKNOWN American Society for Metabolic and Bariatric Surgery Clinical Issues Committee
Oct 6, 2018·Alimentary Pharmacology & Therapeutics·Christian LabenzJörn M Schattenberg
Nov 14, 2018·American Journal of Respiratory and Critical Care Medicine·Omar A MesarwiAtul Malhotra
Dec 1, 2018·Visceral Medicine·Anne-Catherine SchwarzBeat P Müller-Stich
Jan 5, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Almudena Carneiro-BarreraGualberto Buela-Casal

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