PMID: 8942888Nov 1, 1996Paper

Correlation between peripapillary atrophy and optic nerve damage in normal-tension glaucoma

Ophthalmology
K H ParkY Kitazawa

Abstract

To investigate the correlation between peripapillary atrophy and visual field defects as well as optic nerve head configurations in patients with normal-tension glaucoma (NTG). Topographic measurements for peripapillary atrophy and optic nerve head using confocal scanning laser tomography and automated static threshold perimetry were performed on 102 eyes of 51 patients with NTG. Peripapillary atrophy was divided into (1) a central zone (zone Beta) with visible, large choroidal vessels and sclera, and (2) a peripheral zone (zone Alpha) with irregular hyper- and hypopigmentation. The area, angular extent around the disc, and radial extent of each zone were measured. The area and extent of zone Beta increased significantly with increasing visual field defects expressed in terms of mean deviation, corrected pattern standard deviation, central visual field defects within 5 degrees of fixation, and superior hemifield defects (r = 0.3770-0.5291, P < 0.01). The angular extent of zone Beta represented localized field defects better (r = 0.5217, P < 0.001) than diffuse field defects (r = -0.3770, P < 0.01). Zone Beta significantly correlated with optic nerve head topography. Intraindividual right-left-side differences of corrected patte...Continue Reading

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Citations

Oct 17, 2012·Japanese Journal of Ophthalmology·Hiroko TakasakiKazuhisa Sugiyama
May 30, 2001·Survey of Ophthalmology·G A Cioffi
Feb 20, 1999·Survey of Ophthalmology·J B JonasS Panda-Jonas
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Nov 27, 2015·Ophthalmology·Mi Sun SungSang Woo Park
Feb 6, 2010·Ophthalmology·Christopher C TengJeffrey M Liebmann
Jul 27, 2007·American Journal of Ophthalmology·Liang XuJost B Jonas
Feb 4, 2012·Clinical & Experimental Ophthalmology·Kazuyuki HirookaFumio Shiraga
Sep 19, 2012·IEEE Transactions on Medical Imaging·Jun ChengSeang Mei Saw
Apr 3, 2004·American Journal of Ophthalmology·Wido M Budde, Jost B Jonas
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Jul 20, 2018·Investigative Ophthalmology & Visual Science·Soh Youn SuhJoseph L Demer
Jul 24, 2018·Cutaneous and Ocular Toxicology·Cahit Yavuz, Muammer Ozcimen

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