Correlation between PET/CT results and histological and immunohistochemical findings in breast carcinomas

Radiologia brasileira
Almir Galvão Vieira BitencourtCynthia Aparecida Bueno de Toledo Osório

Abstract

To correlate the results of (18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) performed with a specific protocol for assessment of breasts with histological/immunohistochemical findings in breast carcinoma patients. Cross-sectional study with prospective data collection, where patients with biopsy-confirmed breast carcinomas were studied. The patients underwent PET/CT examination in prone position, with a specific protocol for assessment of breasts. PET/CT findings were compared with histological and immunohistochemical data. The authors identified 59 malignant breast lesions in 50 patients. The maximum diameter of the lesions ranged from 6 to 80 mm (mean: 32.2 mm). Invasive ductal carcinoma was the most common histological type (n = 47; 79.7%). At PET/CT, 53 (89.8%) of the lesions demonstrated anomalous concentrations of (18)F-FDG, with maximum SUV ranging from 0.8 to 23.1 (mean: 5.5). A statistically significant association was observed between higher values of maximum SUV and histological type, histological grade, molecular subtype, tumor diameter, mitotic index and Ki-67 expression. PET/CT performed with specific protocol for assessment of breasts has demonstrated good sens...Continue Reading

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Citations

Jan 23, 2016·AJR. American Journal of Roentgenology·Almir G V BitencourtElvira F Marques
Jan 27, 2016·Radiologia brasileira·Laís Bastos PessanhaMelissa Bozzi Nonato Mello
May 4, 2016·Radiologia brasileira·Ellyete de Oliveira Canella
Nov 8, 2016·Radiologia brasileira·Bruna Maria ThompsonMaria Regina Vianna
Nov 8, 2016·Radiologia brasileira·Giorge Pereira SampaioAlair Augusto Sarmet Moreira Damas Dos Santos
Nov 8, 2016·Radiologia brasileira·Ruffo Freitas-JuniorRosemar Macedo Sousa Rahal
Jul 25, 2019·Future Oncology·Nicoletta UrbanoOrazio Schillaci

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Methods Mentioned

BETA
biopsy
surgical resection
biopsies

Software Mentioned

SPSS

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