Correlation between redefined optical coherence tomography parameters and best-corrected visual acuity in non-resolving central serous chorioretinopathy treated with half-dose photodynamic therapy

PloS One
Thomas J van RijssenCamiel J F Boon

Abstract

To assess parameters on optical coherence tomography (OCT), and their correlation with best-corrected visual acuity (BCVA) in patients with non-resolving central serous chorioretinopathy (CSC). For 25 non-resolving CSC patients treated with photodynamic therapy (PDT), the thickness of retinal layers was assessed on the foveal spectral-domain (SD) OCT scan. Evaluated OCT parameters included the central retinal thickness (CRT), defined as the internal limiting membrane (ILM) to ellipsoid zone (EZ) distance, and the second band thickness (SBT), defined as the EZ to hyperreflective subretinal accumulation distance. Integrity of the external limiting membrane (ELM) and the EZ bands was also determined. These parameters, along with BCVA and CRT measured automatically by SD-OCT device software were obtained before PDT, after PDT, and at final visit. After Bonferroni correction, a p-value <0.007 was considered statistically significant. Twenty-five patients could be included at last visit before PDT and first visit after PDT. At final visit, 24 patients could be included, since 1 patients was lost to follow-up. Mean CRT was 112 μm at last visit before PDT, 118 μm at first visit after PDT (p = 0.030), and 127 μm at final visit (p<0.001c...Continue Reading

References

Mar 17, 2004·Ophthalmology·Robert HaimoviciUNKNOWN Central Serous Chorioretinopathy Case-Control Study Group
Jan 18, 2005·American Journal of Ophthalmology·Felice Cardillo PiccolinoMarilisa Manea
Dec 31, 2005·Investigative Ophthalmology & Visual Science·Radouil TzekovJames Burke
Jan 7, 2006·Acta Ophthalmologica Scandinavica·Maria WangMichael Larsen
Nov 22, 2007·American Journal of Ophthalmology·Hidetaka MatsumotoTaku Sato
Oct 14, 2008·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Minoru FurutaShoji Kishi
Feb 3, 2009·Nature Neuroscience·Jin-Shan WangVladimir J Kefalov
Feb 13, 2010·Japanese Journal of Ophthalmology·Yumiko OjimaNagahisa Yoshimura
Feb 27, 2013·Glia·Andreas Reichenbach, Andreas Bringmann
Apr 24, 2014·Ophthalmology·Giovanni StaurenghiUNKNOWN International Nomenclature for Optical Coherence Tomography (IN•OCT) Panel
Jun 1, 2015·Progress in Retinal and Eye Research·Alejandra DaruichFrancine Behar-Cohen
Nov 22, 2015·Clinical & Experimental Ophthalmology·Lingwei William TaoChi D Luu

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Citations

Sep 11, 2019·Journal of Clinical Medicine·Maciej GawęckiAndrzej Grzybowski
May 28, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Thomas J van RijssenCamiel J F Boon
Oct 30, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Thomas J van RijssenCamiel J F Boon
Jul 19, 2019·Progress in Retinal and Eye Research·Thomas J van RijssenCamiel J F Boon
May 15, 2020·Progress in Retinal and Eye Research·Rebecca KayeAndrew Lotery
Aug 21, 2021·Klinische Monatsblätter für Augenheilkunde·Lieselotte BergerSuzanne Yzer

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Software Mentioned

SPSS Statistics
OCT
SD
Heidelberg Eye Explorer
OCT device

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