PMID: 32524130Jun 12, 2020Paper

Correlation between salivary stress markers and clinical parameters of periodontitis

Shanghai kou qiang yi xue = Shanghai journal of stomatology
Qin YuTao Zhu

Abstract

To investigate the correlation between salivary stress markers chromogranin A (CgA), cortisol, α-amylase, β-endorphin and clinical parameters of periodontitis, including sulcus bleeding index (SBI), periodontal probing depth (PD) and attachment loss (AL). A total of 105 patients with chronic periodontitis (periodontitis group) and 105 healthy individuals (control group) visiting our hospital from December 2017 to December 2018 were selected. Indicators including CgA, cortisol, α-amylase, β-endorphin levels, SBI, PD, and AL were detected in both groups, and the correlation among them was determined by Pearson's analysis, multivariate logistic regression was used to analyze the risk factors associated with periodontitis using SPSS 22.0 software package. The levels of CgA, cortisol, α-amylase and β-endorphin in the periodontitis group were significantly higher than those in the control group (P<0.05). SBI, PD and AL in the periodontitis group were significantly higher than those in the control group (P<0.05). The levels of CgA, cortisol, α-amylase and β-endorphin in saliva were positively correlated with SBI, PD, and AL (P<0.05). CgA, cortisol, α-amylase, and β-endorphin were independent risk factors for periodontitis (P<0.05). Sa...Continue Reading

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