Correlation between sonographic findings and clinicopathologic and biologic features of pure ductal carcinoma in situ in 691 patients

AJR. American Journal of Roentgenology
Marion E ScogginsWei T Yang

Abstract

The objective of our study was to compare the sonographic features of pure ductal carcinoma in situ (DCIS) lesions with the initial clinical presentation and histopathologic findings. The images and records of 691 patients with pure DCIS who underwent preoperative mammography and whole-breast sonography as part of staging workup in a single institution from January 1, 1996, through July 31, 2009, were reviewed. The BI-RADS sonography lexicon was used when reviewing the sonographic studies. Histopathologic features recorded included estrogen receptor (ER) status, nuclear grade, and presence or absence of comedonecrosis. Statistical comparisons were made using the Student t test, chi-square test, Fisher exact test, Kruskal-Wallis or Wilcoxon rank sum test, multiple logistic regression analysis, and Pearson correlation coefficient. A total of 304 (44%) tumors were visible on mammography and sonography; 315 (46%), on mammography only; 58 (8%), on sonography only; and 14 (2%), on neither mammography nor sonography. The most common sonographic appearance of DCIS was an irregular hypoechoic mass with indistinct margins and normal posterior features that was indistinguishable from invasive carcinoma. Patients with symptomatic high-nucl...Continue Reading

References

Apr 7, 1988·The New England Journal of Medicine·S J SchnittJ R Harris
Nov 1, 1993·Breast Cancer Research and Treatment·D L Page, W D Dupont
Jan 1, 1997·European Journal of Radiology·G RizzattoD Macorig
Sep 2, 1998·Radiology·L LibermanA F Abramson
Apr 17, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N BijkerM J van de Vijver
May 10, 2001·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·B E HashimotoV J Picozzi
Jan 18, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Polya SamardarJohn D Wilson
Mar 16, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Woo Kyung MoonJung-Gi Im
Mar 21, 2003·AJR. American Journal of Roentgenology·Mary Scott SooEric L Rosen
Jul 24, 2003·AJR. American Journal of Roentgenology·Laura LibermanLee K Tan
Sep 23, 2003·The British Journal of Radiology·S-C ChenS Hsueh
Dec 20, 2003·AJR. American Journal of Roentgenology·Wei Tse Yang, Gary M K Tse
Aug 20, 2005·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Takeshi NagashimaMasaru Miyazaki
Oct 8, 2005·Advances in Anatomic Pathology·Sharon Nofech-MozesWedad Hanna
Nov 7, 2007·The Breast Journal·Eric L RosenConstance D Lehman
Jan 24, 2008·AJR. American Journal of Roentgenology·Hee Jung ShinOn Koo Cho
Dec 3, 2008·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Junko TakeiYukihisa Saida
Jun 24, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jae Hwan KimDu Hwan Choe
Jul 4, 2009·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Ayumi IzumoriAkira Sato
Jan 15, 2010·Journal of the National Cancer Institute·Beth A VirnigRobert L Kane
Mar 23, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Francesco SardanelliRobin Wilson
Oct 1, 2010·Annals of Surgical Oncology·Nimmi AroraMonica Morrow
Nov 26, 2010·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ji-Sung ParkJi-Hwa Ryu
May 10, 2011·Journal of Cancer·Sara A Lari, Henry M Kuerer
Mar 7, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D Craig AllredNorman Wolmark
Jan 17, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Lilian C WangEllen B Mendelson
Jan 25, 2013·AJR. American Journal of Roentgenology·Abid IrshadAmy Campbell
Mar 26, 2013·AJR. American Journal of Roentgenology·Won Hwa KimSeung Ja Kim
Oct 5, 2013·Medical Physics·Ruey-Feng ChangWoo Kyung Moon

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Mar 18, 2020·Radiology·Ga Young YoonEun Young Chae
Jan 8, 2021·Journal of Ultrasound·Marco MoschettaCristina Ferrari

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