Correlation between the serum luteinizing hormone to folliclestimulating hormone ratio and the anti-Müllerian hormone levels in normo-ovulatory women

Journal of Korean Medical Science
Jong Eun LeeEung Gi Min

Abstract

Serum anti-Müllerian hormone (AMH) levels are regarded as an age-specific marker for predicting the ovarian reserve in women of reproductive age. Some studies have shown that the luteinizing hormone (LH)/follicle stimulating hormone (FSH) ratio can be used as a predictor of ovarian reserve. The purpose of this study was to assess the variation of LH/FSH ratio with aging and to evaluate the correlation between serum LH/FSH ratio and AMH levels as a predictor of the ovarian reserve in normo-ovulatory women. We retrospectively analyzed the day 3 serum hormone levels in 1,251 patients (age range: 20-50 yr) between January 2010 and January 2011. We divided the patients into 6 groups according to their age. Relation between serum AMH level and LH/FSH ratio was analyzed statistically. The serum AMH level was inversely correlated with age (r = -0.400, P < 0.001). A significant negative correlation was found between serum LH/FSH ratio and age (r = -0.213, P < 0.001). There was a significant partial correlation between serum LH/FSH ratio and AMH level when adjusted by age (r = 0.348, P < 0.001). The LH/FSH ratio could be considered as a useful marker for the ovarian reserve and could be applied to the clinical evaluation with AMH.

References

Oct 23, 2001·Journal of Assisted Reproduction and Genetics·G BarrosoS J Muasher
Feb 16, 2006·Reproductive Biomedicine Online·Ilse A J van RooijEgbert R te Velde
Jun 3, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Eric Scott SillsAnthony P H Walsh
Mar 23, 2010·Fertility and Sterility·Ettore GuastellaEnrico Carmina
Aug 28, 2010·Reproductive Biomedicine Online·A La MarcaD Toniolo
Dec 15, 2010·Human Reproduction·Majedah Al-AzemiWilliam Ledger
Jan 29, 2011·Reproductive Biomedicine Online·David H BaradNorbert Gleicher
Feb 9, 2011·Reproductive Biology and Endocrinology : RB&E·Norbert GleicherDavid H Barad
Dec 21, 2011·Journal of Assisted Reproduction and Genetics·Berna SeckinGulnur Ozaksit
Mar 3, 2012·Clinical and Experimental Reproductive Medicine·Ji Hee YooInn Soo Kang

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Citations

Jun 16, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Paolo E Levi-SettiValeria Liprandi
Aug 30, 2018·Thyroid : Official Journal of the American Thyroid Association·Berna EvranosBekir Cakir
Nov 21, 2020·Reproductive Biomedicine Online·Christine I VaitsopoulouBasil C Tarlatzis

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Software Mentioned

Statistical Package for the Social Sciences
SPSS

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