Correlation between ultrasound-diagnosed non-alcoholic fatty liver and periodontal condition in a cross-sectional study in Japan

Scientific Reports
Takahiro IwasakiTakaaki Tomofuji

Abstract

This cross-sectional study investigated the relationship between periodontal condition and ultrasound-diagnosed non-alcoholic fatty liver disease (NAFLD) in a Japanese oral health check population. A total of 1226 consecutive participant were enrolled in the study. Abdominal ultrasonography was applied to diagnose NAFLD. Of the study participants, 339 (27.7%) had ultrasonography-diagnosed NAFLD. The participants with NAFLD had a significantly higher prevalence of probing pocket depth (PPD) ≥ 4 mm (86.7%) than those without NAFLD (72.9%) (p < 0.05). After adjusting for gender, age, Brinkman index, regular exercise habits, body mass index, number of teeth present, presence of periodontitis, blood pressure, and serum parameters, there was a statistically significant difference in the adjusted odds ratios of having PPD ≥ 4 mm for NAFLD (Odds ratio = 1.881, 95% confidence interval 1.184-2.987, p < 0.01). Having PPD ≥ 4 mm may be a risk factor for ultrasound-diagnosed NAFLD in this cross-sectional study of a Japanese oral health check population.

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Citations

Jun 21, 2019·Journal of Oral Science·Takahiro IwasakiTakaaki Tomofuji
Oct 26, 2018·Clinical Oral Investigations·Mohammad Sultan AlakhaliEsam Halboub
Mar 11, 2020·International Journal of Environmental Research and Public Health·Minako HadaTakaaki Tomofuji
Mar 6, 2019·Scientific Reports·Takahiro IwasakiTakaaki Tomofuji
Sep 22, 2019·International Journal of Environmental Research and Public Health·Valerio RosatoMarcello Persico
Dec 29, 2020·Journal of Clinical Periodontology·Kei KuroeYoshihisa Yamashita
Mar 20, 2019·Archives of Oral Biology·Toshiki YonedaManabu Morita
May 1, 2021·International Journal of Molecular Sciences·Masahiro HatasaSayaka Katagiri
May 25, 2021·Archives of Toxicology·Joost BoeckmansTamara Vanhaecke
Dec 11, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael H LeMindie H Nguyen

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Methods Mentioned

BETA
biopsy
imaging technique

Software Mentioned

SPSS

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