PMID: 7021504Jul 1, 1981Paper

Correlation of airway resistance with forced random noise resistance parameters

Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
R L PimmelP A Bromberg

Abstract

The correlation between airway resistance (Raw) measured in a plethysmograph and three respiratory resistance parameters measured by forced random noise was evaluated. Forced random noise resistance parameters were the average resistance between 5 and 9 hz (R5-9), the average resistance between 20 and 24 Hz (R20-24), and the extrapolated resistance at 1 Hz (R1). We studied 22 healthy, nonsmoking subjects, 10 of whom had a history suggesting childhood asthma. Serial measurements were made after inhalation of aerosols containing increasing concentrations of methacholine of aerosols containing increasing concentrations of methacholine to obtain data in various stages of bronchoconstriction. There was a broad range of responsiveness to methacholine; the ratio of the peak to base-line values of Raw ranged from 1.1 to 6.3. R1, R5-9, and R20-24 were related to Raw by linear regression analysis. R1 and R5-9 showed excellent correlation with Raw (r = 093 and 4=0.91, respectively); R20-24 showed much poorer correlation (r = 0.62). The slopes of the regression equations for R1 and R5-9 were 1.56 and 0.51, respectively; thus neither provided an exact measure of Raw. The data appear to be consistent with a model in which most of the methach...Continue Reading

Citations

Mar 1, 1989·Equine Veterinary Journal·S S Young, L W Hall
Oct 1, 1983·Environmental Health Perspectives·J J O'Neil, J A Raub
Nov 20, 2001·Medical & Biological Engineering & Computing·D MacLeod, M Birch
Jan 1, 1988·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·E F WoutersB F Visser
Jan 1, 1981·Annals of Biomedical Engineering·R Pimmel, J M Fullton
Jan 1, 1989·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·E F WoutersB F Visser
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·C DelacourtB Housset
Jan 1, 1993·Veterinary Research Communications·C ClercxK P Van de Woestijne
Nov 1, 1984·British Journal of Industrial Medicine·M J SepulvedaJ B Cocke
Aug 10, 2001·Journal of Aerosol Medicine : the Official Journal of the International Society for Aerosols in Medicine·M KohlhäuflJ Heyder
Mar 1, 1984·The Annals of Otology, Rhinology, and Laryngology·J M FulltonP A Bromberg

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.