Correlation of clinical neuromusculoskeletal and central somatosensory performance: variability in controls and patients with severe and mild focal hand dystonia

Neural Plasticity
N N BylAlison L McKenzie

Abstract

Focal hand dystonia (FHd) is a recalcitrant, disabling movement disorder, characterized by involuntary co-contractions of agonists and antagonists, that can develop in patients who overuse or misuse their hands. The aim of this study was to document clinical neuromusculoskeletal performance and somatosensory responses (magnetoencephalography) in healthy controls and in FHd subjects with mild versus severe hand dystonia. The performance of healthy subjects (n = 17) was significantly better than that of FHd subjects (n =17) on all clinical parameters. Those with mild dystonia (n = 10) demonstrated better musculoskeletal skills, task-specific motor performance, and sensory discrimination, but the performance of sensory and fine motor tasks was slower than that of patients with severe dystonia. In terms of somatosensory evoked field responses (SEFs), FHd subjects demonstrated a significant difference in the location of the hand representation on the x and y axes, lower amplitude of SEFs integrated across latency, and a higher ratio of mean SEF amplitude to latency than the controls. Bilaterally, those with FHd (mild and severe) lacked progressive sequencing of the digits from inferior to superior. On the affected digits, subjects w...Continue Reading

Citations

Oct 14, 2005·Current Treatment Options in Neurology·Terence D Sanger
Jan 26, 2012·Current Opinion in Rheumatology·Nancy N Byl
Jul 16, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J-P Bleton
Jan 27, 2009·Physical Therapy·Regina T Harbourne, Nicholas Stergiou
Nov 24, 2004·The Journal of Orthopaedic and Sports Physical Therapy·Ann E BarrBrian D Clark
Nov 23, 2007·Disability and Rehabilitation·Geoffrey Sheean
Aug 2, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Rebecca DolbergSrikantan S Nagarajan
Dec 18, 2010·Neurología : publicación oficial de la Sociedad Española de Neurología·R AránguizM León
Apr 25, 2009·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Alison L McKenzieNancy Byl
Mar 13, 2009·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Sarah B GoldmanAmanda Antczak
Oct 12, 2014·Gait & Posture·Shiu-Ling ChiuLi-Shan Chou
Nov 13, 2012·Experimental Neurology·Daniele BelvisiAlfredo Berardelli
Aug 24, 2007·Current Opinion in Neurobiology·Jonathan B FritzShihab A Shamma
Feb 22, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Simon MetenouDiane Wallace Taylor
Feb 13, 2004·The Journal of Bone and Joint Surgery. American Volume·Peter C Amadio
Jan 5, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Michael ZemlinKarl Bauer
Mar 13, 2009·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Filippo CogiamanianAlberto Priori

❮ Previous
Next ❯

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
V CandiaWilliam Ray
Movement Disorders : Official Journal of the Movement Disorder Society
Stephen ButterworthGuy V Sawle
© 2022 Meta ULC. All rights reserved