Jun 1, 1995

Correlation of CSF 5-HIAA concentration with sociality and the timing of emigration in free-ranging primates

The American Journal of Psychiatry
P T MehlmanM Linnoila

Abstract

The purpose of this study was to examine the relationship between behavior and serotonin in nonhuman primates. During a routine capture and medical examination, 26 adolescent male rhesus macaques (Macaca mulatta) were selected as subjects from a free-ranging population of 4,500 rhesus monkeys inhabiting a 475-acre sea island. Blood samples (N = 23) and CSF samples (N = 22) were obtained, and each subject was fitted with a radio transmitter collar for rapid location. The subjects were released into their social groups, and quantitative behavioral observations were made over a 3-month period. CSF 5-hydroxyindoleacetic acid (5-HIAA) concentration was positively correlated with three measures of sociality: 1) total time spent grooming others, 2) total time spent in close proximity to other group members, and 3) mean number of neighbors within a 5-m radius. In addition, CSF 5-HIAA concentration was positively correlated with age at emigration from the natal group (in months). In adolescent male rhesus macaques living in naturalistic settings, CSF 5-HIAA concentration is positively correlated with affiliative sociality. Rhesus males with low CSF 5-HIAA concentrations exhibit less social competence and emigrate from their social group...Continue Reading

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Mentioned in this Paper

Behavior, Animal
Nonhuman primate
Serotonin Measurement
Serotonin
Preening
Harassment, Non-Sexual
Homing Behavior
Primates
Hydroxyindoleacetic Acid
Macaca mulatta

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