Correlation of CT imaging and histology to guide bone graft selection in scaphoid non-union surgery

Archives of Orthopaedic and Trauma Surgery
Gernot SchmidleMarkus Gabl

Abstract

For the treatment of scaphoid non-unions (SNU), different surgical techniques, including vascularized and non-vascularized bone grafts, are applied. Besides stability, vascularity, and the biological situation at the non-union site are important for healing and the appropriate choice of treatment. We assessed the healing potential of SNUs by histological parameters and compared it to CT parameters of bone structure and fracture location. Based on the results, we developed a CT classification and a treatment algorithm to impact graft selection in SNU surgery. Preoperative 2D-CT reformations of 29 patients were analyzed for trabecular structure, sclerosis, and fragmentation of the proximal fragment. The fracture location was assessed on 3D-CT reconstructions and grouped in three zones depending on the potential blood supply. Samples were taken during surgery for histological evaluation. Histological parameters of bone healing were defined and a bone healing capacity score (BHC), reflecting histological bone viability, was calculated. CT findings were compared to BHC, age of SNU, and time to union. Cases with trabecular structure and without fragmentation showed a statistically significant higher BHC. Time to union was significant...Continue Reading

References

Feb 1, 1992·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·T ImaedaN Makino
May 1, 1991·The Journal of Hand Surgery·R NakamuraN Hayakawa
Jan 1, 1996·Archives of Orthopaedic and Trauma Surgery·G Inoue, M Sakuma
Aug 14, 1999·The Journal of Hand Surgery·F SchuindG Sennwald
Dec 22, 1999·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·V V DesaiN J Barton
Jan 11, 2000·AJR. American Journal of Roentgenology·L CerezalF del Piñal
May 16, 2000·The Journal of Hand Surgery·H MoritomoR M Patterson
Sep 23, 2000·AJR. American Journal of Roentgenology·P L Munk, M J Lee
Dec 1, 2000·Der Unfallchirurg·H KrimmerT Herbert
Aug 28, 2001·The Journal of Bone and Joint Surgery. British Volume·J S DawsonT R Davis
Jul 20, 2002·The Journal of Hand Surgery·Gregory A MerrellJoseph F Slade
Oct 28, 2003·Plastic and Reconstructive Surgery·Victoria S Pao, James Chang
Sep 1, 2004·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·A K SinghN D Downing
Apr 8, 2006·Clinical Orthopaedics and Related Research·Joseph F Slade, Seth D Dodds
Dec 5, 2006·The Journal of Bone and Joint Surgery. American Volume·Santiago Lozano-CalderónDavid Ring
Jul 2, 2008·The Journal of Hand Surgery·Guowei Qu, Herbert P von Schroeder
Jul 29, 2008·The Journal of Hand Surgery·Kenji Kawamura, Kevin C Chung
Nov 6, 2008·The Journal of Hand Surgery·Hisao MoritomoKazuomi Sugamoto
Dec 2, 2009·Archives of Orthopaedic and Trauma Surgery·Susanne ReinStefan Weindel
Jun 26, 2010·Journal of Orthopaedic Trauma·Stephanie A BernardMichael G Heckman
Jul 14, 2010·The Journal of Hand Surgery, European Volume·K MegerleH Krimmer
May 1, 2012·The Journal of Hand Surgery·Geert A BuijzeDavid Ring
Jun 1, 2012·Seminars in Musculoskeletal Radiology·Mihra S TaljanovicJoseph E Sheppard
Jul 7, 2014·The Journal of Hand Surgery·Eli T Sayegh, Robert J Strauch
Jun 9, 2015·Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·Steven E R Hovius, Tim de Jong
Jun 28, 2015·The Journal of Hand Surgery·Richard M PinderMark Brewster
Apr 14, 2016·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·R SchmittUNKNOWN Deutsche Gesellschaft für Unfallchirurgie (DGU, Deutsche Gesellschaft für Orthopädie und Orthopädische Chirurgie (DGOOC), De
Oct 28, 2016·Der Orthopäde·M F LangerB Wieskötter
Apr 4, 2017·Archives of Orthopaedic and Trauma Surgery·Moritz DustmannNikolaus Wachter
Sep 13, 2017·The Journal of Hand Surgery, European Volume·Jihyeung KimGoo Hyun Baek
Sep 19, 2017·Archives of Orthopaedic and Trauma Surgery·S QuadlbauerM Leixnering
Sep 26, 2017·The Journal of Hand Surgery, European Volume·Schneider K RancyUNKNOWN Scaphoid Nonunion Consortium
Mar 1, 2018·Journal of Anatomy·Gernot SchmidleMarkus Gabl

❮ Previous
Next ❯

Citations

May 28, 2019·Archives of Orthopaedic and Trauma Surgery·Isabella M MehlingM Sauerbier
Aug 23, 2019·Operative Orthopädie und Traumatologie·S QuadlbauerM Leixnering
Sep 30, 2020·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deut·Karlheinz KalbKarl-Josef Prommersberger
Sep 30, 2020·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deut·Stefan Georg FodorMarion Mühldorfer-Fodor
Sep 30, 2020·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deut·Gernot SchmidleRohit Arora
Sep 30, 2020·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deut·Tobias KastenbergerRohit Arora
Mar 4, 2020·Archives of Orthopaedic and Trauma Surgery·Marco KellerRohit Arora

❮ Previous
Next ❯

Methods Mentioned

BETA
scanning electron microscopy

Software Mentioned

SPSS
R

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.