Correlation of fasting serum apolipoprotein B-48 with coronary artery disease prevalence

European Journal of Clinical Investigation
Daisaku MasudaS Yamashita

Abstract

Postprandial hyperlipidemia partially refers to the postprandial accumulation of chylomicrons and chylomicron remnants (CM-R). Many in vitro studies have shown that CM-R has highly atherogenic properties, but consensus is lacking on whether CM-R accumulation correlates with the development of atherosclerotic cardiovascular diseases. We investigated the correlation between CM-R accumulation and the prevalence of coronary artery disease (CAD). Subjects who received a coronary angiography and did not take any lipid-lowering drugs (n = 189) were enrolled. Subjects with coronary artery stenosis (≥ 75%) were diagnosed as CAD. Biochemical markers for glucose and lipid metabolism including fasting apolipoprotein (apo) B-48 concentration were compared between CAD patients (n = 96) and age-, sex-, and body mass index (BMI)-matched non-CAD subjects without overt coronary stenosis (< 75%) (n = 67). We tried to determine which metabolic parameters were correlated with the prevalence of CAD by multiple logistic regression analysis, and whether or not the combination of high apo B-48 and other coronary risk factors (high triglyceride, low HDL-C, high HbA1c or low adiponectin levels) increased the prevalence of CAD. Fasting serum apo B-48 leve...Continue Reading

References

Sep 1, 1979·Circulation·D B Zilversmit
Dec 3, 1999·Journal of Internal Medicine·F Karpe
Feb 28, 2001·American Journal of Epidemiology·H IsoY Komachi
Jan 14, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Masahiro KumadaUNKNOWN Osaka CAD Study Group. Coronary artery disease
Apr 3, 2003·Journal of Lipid Research·Naohiko SakaiYuji Matsuzawa
Jul 26, 2003·Clinical Chemistry and Laboratory Medicine : CCLM·Sebely PalJohn Mamo
Jan 8, 2004·Atherosclerosis·Jun-ichi FunadaHiroshi Akutsu
Oct 29, 2005·Metabolism: Clinical and Experimental·René ValeroHenri Portugal
Jan 6, 2006·Journal of Atherosclerosis and Thrombosis·Yuji Matsuzawa
Sep 11, 2007·Journal of Atherosclerosis and Thrombosis·Tamio TeramotoUNKNOWN Japan Atherosclerosis Society (JAS) Committee for Epidemiology and Clinical Management of Atherosclerosis
Jul 18, 2008·Diabetes Research and Clinical Practice·Kyoko TanimuraShinichi Oikawa
Oct 8, 2008·European Journal of Clinical Investigation·D C ChanP H R Barrett
Jun 6, 2009·European Journal of Clinical Investigation·D MasudaS Yamashita
Jun 27, 2009·Journal of Atherosclerosis and Thrombosis·Yoshio Fujioka, Yuichi Ishikawa
Aug 29, 2009·Journal of Atherosclerosis and Thrombosis·Makoto KinoshitaTamio Teramoto
Jun 15, 2010·Journal of Atherosclerosis and Thrombosis·José C SandovalShizuya Yamashita
Sep 29, 2011·Journal of Atherosclerosis and Thrombosis·Daisaku MasudaShizuya Yamashita
Oct 1, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Hiroyuki HanadaShizuya Yamashita

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Citations

Nov 20, 2012·Current Opinion in Lipidology·Mary J Malloy, John P Kane
Feb 11, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Jan BorénMarja-Riitta Taskinen
Feb 13, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Josep JulveFrancisco Blanco-Vaca
Sep 4, 2012·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Juan Patricio Nogueira, Fernando Daniel Brites
Feb 19, 2014·Atherosclerosis·Changting XiaoGary F Lewis
Feb 23, 2013·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kenta MoriKen-ichi Hirata
May 26, 2015·Clinical Lipidology·Jixin ZhongSanjay Rajagopalan
Nov 11, 2016·Journal of Atherosclerosis and Thrombosis·Daisaku Masuda, Shizuya Yamashita
Nov 11, 2016·Journal of Atherosclerosis and Thrombosis·Daisaku Masuda, Shizuya Yamashita
Nov 13, 2014·Journal of Lipid Research·Emile Levy
Dec 13, 2017·European Journal of Clinical Investigation·Benjamin BurggraafManuel Castro Cabezas
Jun 23, 2018·Arteriosclerosis, Thrombosis, and Vascular Biology·Osamu KuriharaWataru Shimizu
Jan 30, 2019·Current Opinion in Endocrinology, Diabetes, and Obesity·Giuliano GenerosoMarcio S Bittencourt
Aug 7, 2017·Journal of Atherosclerosis and Thrombosis·Masami SairyoShizuya Yamashita
Nov 27, 2019·Current Pharmaceutical Design·Haizhou WangQiu Zhao
Jun 25, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Harsh AgrawalMichelle A Albert
Feb 28, 2014·Journal of Atherosclerosis and Thrombosis·Daisaku MasudaShizuya Yamashita
Sep 11, 2018·Journal of Atherosclerosis and Thrombosis·Masami SairyoShizuya Yamashita
Aug 5, 2020·Journal of Clinical Medicine·Natalia Mena-VázquezAntonio Fernández-Nebro
Aug 1, 2020·Frontiers in Physiology·Chunmin C Lo, Karen T Coschigano
May 20, 2021·Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis·Teresa PadroLina Badimon

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