Jan 1, 1983

Correlation of human lymphocyte SCE frequency with smoking history

Mutation Research
G K Livingston, R M Fineman

Abstract

Sister-chromatid exchange (SCE) frequency in lymphocytes of 24 active cigarette smokers was compared to that of 24 age and sex matched controls and 7 persons who had stopped smoking an average of 15.6 years. The results indicated that cigarette smoking was associated with a significant elevation (p less than 0.001) in the frequency of SCEs observed in otherwise healthy cigarette smokers. Furthermore, the increase in SCE level was shown to be dose-related to years of exposure when smoking history was measured in cumulative pack-years. The mean SCE frequency of the ex-smokers was not significantly different from nonsmoking controls.

Mentioned in this Paper

Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Sister Chromatid Exchange
Lymphoid Cells
Chromatids
Crossing Over, Genetic
Specimen Type - Lymphocytes
Lymphocyte Count Measurement
Cigar smoker
Lymphocyte

About this Paper

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