journal cover

CORRELATION OF LINEZOLID HAIR CONCENTRATIONS WITH PLASMA EXPOSURE IN PATIENTS WITH DRUG-RESISTANT TB

Antimicrobial Agents and Chemotherapy

Jan 15, 2020

Sean WassermanJohn Metcalfe

Abstract

Plasma drug quantification has a potential role as a biomarker of TB treatment adherence, but utility of short half-life drugs such as linezolid (1) for adherence monitoring may be limited due to rapid plasma clearance and inability to capture long-term dosing.….

Mentioned in this Paper

Plasma
Biological Markers
Pharmacologic Substance
Monitoring - Action
Tuberculosis
Linezolid
1
1
Paper Details
References
  • References5
  • Citations
1
  • References5
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Oxazolidinone Antibiotics

Oxazolidinones are a class of synthetic antibiotics that inhibit the ribosomal 50S subunit of bacteria, thus preventing the formation of the 70S initiation complex essential for bacterial reproduction. Discover the latest research on this class of antibiotics in this feed.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Vitamin K Carboxylase & Antibiotics

Vitamin K-dependent carboxylases generate gamma-carboxyglutamic acids with malonate moieties by modifying glutamate residues in vitamin K-dependent proteins. This feed focuses on cellular mechanisms regulated by vitamin K-dependent carboxylases.

Tuberculosis

Tuberculosis is an infectious disease usually caused by Mycobacterium tuberculosis bacteria. Discover the latest research on tuberculosis here.

Related Papers

The European Respiratory Journal

A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis

The European Respiratory JournalFebruary 14, 2018
Russell R KempkerCharles A Peloquin
The European Respiratory Journal

Linezolid to treat extensively drug-resistant TB: retrospective data are confirmed by experimental evidence

The European Respiratory JournalJuly 3, 2013
Giovanni SotgiuInternational Group for the study of Linezolid
© 2020 Meta ULC. All rights reserved

CORRELATION OF LINEZOLID HAIR CONCENTRATIONS WITH PLASMA EXPOSURE IN PATIENTS WITH DRUG-RESISTANT TB

Antimicrobial Agents and Chemotherapy

Jan 15, 2020

Sean WassermanJohn Metcalfe

PMID: 31932382

DOI: 10.1128/aac.02145-19

Abstract

Plasma drug quantification has a potential role as a biomarker of TB treatment adherence, but utility of short half-life drugs such as linezolid (1) for adherence monitoring may be limited due to rapid plasma clearance and inability to capture long-term dosing.….

Mentioned in this Paper

Plasma
Biological Markers
Pharmacologic Substance
Monitoring - Action
Tuberculosis
Linezolid
1
1

Similar Papers Found In These Feeds

Oxazolidinone Antibiotics

Oxazolidinones are a class of synthetic antibiotics that inhibit the ribosomal 50S subunit of bacteria, thus preventing the formation of the 70S initiation complex essential for bacterial reproduction. Discover the latest research on this class of antibiotics in this feed.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Related Papers

The European Respiratory Journal

A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis

The European Respiratory JournalFebruary 14, 2018
Russell R KempkerCharles A Peloquin
The European Respiratory Journal

Linezolid to treat extensively drug-resistant TB: retrospective data are confirmed by experimental evidence

The European Respiratory JournalJuly 3, 2013
Giovanni SotgiuInternational Group for the study of Linezolid
Paper Details
References
  • References5
  • Citations
1
  • References5
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/correlation-of-linezolid-hair-concentrations-with/31932382