Correlation of prenatal and postnatal ultrasound findings with the incidence of vesicoureteral reflux in children with fetal renal pelvic dilatation

The Journal of Urology
Douglas E CoplenJeffrey M Dicke

Abstract

Up to 1% of prenatal ultrasounds detect renal pelvic dilatation. This dilatation is associated with vesicoureteral reflux but its clinical significance and the necessity for vesicoureteral reflux detection have been questioned. We report an evaluation of fetal renal pelvic dilatation and postnatal sonographic features with the incidence of vesicoureteral reflux. Maximum fetal renal pelvic dilatation was prospectively measured at a single center between 1990 and 2003. Dilatation 4 mm or greater at less than 33 weeks of gestation, or 7 mm or greater at more than 33 weeks was the threshold for inclusion in the study. Postnatal evaluation included ultrasound and voiding cystourethrogram. Postnatal data included vesicoureteral reflux incidence and grade, and caliceal and ureteral dilatation on ultrasound. Of 215 neonates 46 (21%) had vesicoureteral reflux. Mean renal pelvic dilatation was 14.4 mm in those with reflux, which was not statistically different than the mean of 11.8 mm in 169 with a normal voiding cystourethrogram. ROC analysis revealed that fetal renal pelvic dilatation was a poor discriminator of reflux. Reflux was identified in a significantly greater number of neonates with vs without postnatal calicectasis (20% vs 9%...Continue Reading

References

Aug 1, 1991·American Journal of Obstetrics and Gynecology·J E CortevilleJ P Crane
Jul 2, 2002·The Journal of Pediatrics·Khalid IsmailiUNKNOWN Brussels Free University Perinatal Nephrology (BFUPN) Study Group
Jan 17, 2003·The New England Journal of Medicine·Alejandro HobermanEllen R Wald
Jul 29, 2003·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Nigel G AndersonNina Mogridge
Jun 12, 2004·The Journal of Pediatrics·Khalid IsmailiUNKNOWN Brussels Free University Perinatal Nephrology Study Group
Oct 28, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·José Maria Penido SilvaBarbara Caldeira Souza
Jul 27, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Graziela M CoelhoEduardo A Oliveira

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Citations

Jun 5, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Serge GrazioliEric Girardin
Aug 27, 2014·Clinics in Perinatology·Dennis B LiuMax Maizels
Dec 18, 2015·Der Urologe. Ausg. A·J StraubM Riccabona
Jun 16, 2012·European Urology·Serdar TekgülUNKNOWN European Association of Urology
Sep 22, 2009·The Journal of Urology·Cristiane S DiasEduardo A Oliveira
Dec 8, 2019·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fatoş Yalçınkaya, Z Birsin Özçakar

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