PMID: 9451668Feb 6, 1998Paper

Correlation of serum immunoglobulin G Helicobacter pylori antibody titers with histologic and endoscopic findings in patients with dyspepsia

Journal of Clinical Gastroenterology
P-I HsuP-N Hsu

Abstract

Serum immunoglobulin G (IgG) antibody tests are used extensively. We attempted to find out whether the titers of anti-Helicobacter pylori IgG antibody correlated with the degree of macroscopic gastrointestinal damage, the severity of antral gastritis, and the density of antral H. pylori colonization in symptomatic patients. Peripyloric antral biopsy specimens were obtained from 50 consecutive patients with dyspepsia undergoing upper gastrointestinal endoscopy. The macroscopic gastrointestinal damage and the histologic grades of antral gastritis were scored by a modified Lanza scale and Sydney system, respectively. In addition, the densities of antral H. pylori colonization were graded semiquantitatively. Serum IgG antibodies to H. pylori were measured by enzyme-linked immunosorbent assay. Thirty-six (M/F = 29/7) of the 50 patients had H. pylori infection documented by histologic examination or rapid urease test or both. Among the subjects, the IgG antibody titers to H. pylori correlated significantly with the grades of antral polymorphonuclear cell infiltration (p = 0.002) and antral bacterial density (p = 0.01) but not with endoscopic scores, the grades of mononuclear cell infiltration, mucosal atrophy, or intestinal metaplasi...Continue Reading

Associated Clinical Trials

Sep 11, 2015·Ping-I (William) Hsu, M.D.Ping-I (William) Hsu, M.D.
Sep 11, 2015·Ping-I (William) Hsu, M.D.Ping-I (William) Hsu, M.D.
Sep 11, 2015·Ping-I (William) Hsu, M.D.
Nov 30, 2016·Ping-I (William) Hsu, M.D.Ping-I (William) Hsu, M.D.

References

May 1, 1992·The Journal of Infection·A D HarriesC A Hart
Oct 17, 1991·The New England Journal of Medicine·J ParsonnetR K Sibley
May 1, 1991·Journal of Gastroenterology and Hepatology·A B Price
Aug 1, 1989·Journal of Clinical Microbiology·F MégraudD Q Hoa
Sep 1, 1995·Gastrointestinal Endoscopy·C J Gostout
Jul 1, 1996·Journal of Gastroenterology and Hepatology·T AzumaY Kohli

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Citations

May 5, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Y H GongY Yuan
Jan 18, 2006·Epidemiology and Infection·A M VollaardJ T Van Dissel
Jan 13, 2000·The British Journal of Surgery·M R KellH P Redmond
Aug 30, 2011·Journal of Gastroenterology and Hepatology·Feng-Woei TsayDeng-Chyang Wu
Sep 3, 2002·Clinical and Diagnostic Laboratory Immunology·Tseng-Shing ChenShou-Dong Lee
Nov 19, 2010·World Journal of Gastroenterology : WJG·Pei-Jung LuHui-Chun Chen
Aug 14, 2012·Gastroenterology Research and Practice·Sung-Shuo KaoFeng-Woei Tsay
May 19, 2011·Applied Biochemistry and Biotechnology·Ram Sarup SinghAshok Kumar Tiwary
Dec 26, 2012·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Tzung-Jiun TsaiFeng-Woei Tsay
Aug 19, 2007·European Journal of Clinical Investigation·P I HsuG H Lo
Apr 26, 2008·European Journal of Clinical Investigation·P I HsuK H Lai
Oct 13, 2006·European Journal of Clinical Investigation·D C WuH H Tseng
Mar 29, 2001·São Paulo Medical Journal = Revista Paulista De Medicina·S K OgataA M Santos
May 11, 2005·World Journal of Gastroenterology : WJG·Ping-I HsuAngela Chen
Feb 15, 2002·Clinical Otolaryngology and Allied Sciences·L J SkinnerH P Burns
Mar 10, 2016·Journal of Korean Medical Science·Ji-Hyun SeoKwang-Ho Rhee
Feb 28, 2007·The American Journal of Gastroenterology·Ping-I HsuHui-Chun Chen
Nov 4, 2008·Journal of Pediatric Gastroenterology and Nutrition·Carolina A SerranoPaul R Harris
Dec 14, 1999·The British Journal of Surgery·M R KellH P Redmond
Feb 10, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ping-I HsuPei-Jung Lu

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