Abstract
In patients with lipodermatosclerosis caused by chronic venous disease of the lower limb, the skin capillaries show proliferation and convolution. To our knowledge, no previous attempt has been made to correlate the clinical severity of venous disease based on the CEAP classification with the capillary morphology changes. The purpose of this study was to correlate the clinical severity with the capillary morphology changes in patients with chronic venous disease by using capillary microscopy and to explore the significance of atypical capillary morphology in patients with uncomplicated varicose veins. Patients attending the vascular clinic for management of chronic venous disease were examined clinically and by duplex ultrasonography scans, and they were assigned to the appropriate CEAP clinical stage (C1, n = 15; C2, n = 20; C3, n = 15; C4a, n = 15; C4b, n = 15; C5, n = 15). Also studied were 10 control subjects with no arterial or venous disease of the lower limb. In part 1 of the study, a capillary microscope was used to obtain digital images of the skin microcirculation in the gaiter region. The capillary density and capillary convolutions were counted in a 2.4 mm2 region of skin. In part 2 of the study, a further 33 C2 and...Continue Reading
References
Aug 1, 1986·Archives of Internal Medicine·A BollingerW Siegenthaler
Oct 1, 1984·Clinical Physiology·B Fagrell, G Lundberg
May 1, 1981·The British Journal of Surgery·K G BurnandN L Browse
Nov 1, 1995·The Journal of Surgical Research·P J PappasR W Hobson
Mar 1, 1993·The British Journal of Dermatology·O LuetolfP S Mortimer
Mar 1, 1995·International Journal of Microcirculation, Clinical and Experimental·R BullP S Mortimer
Sep 1, 1996·International Journal of Microcirculation, Clinical and Experimental·M JüngerG Rassner
May 1, 1997·International Journal of Microcirculation, Clinical and Experimental·M FischerU K Franzeck
Aug 1, 1997·Journal of Vascular Surgery·M SaharayP D Coleridge Smith
Jun 4, 1998·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M SaharayP D Coleridge Smith
Jul 9, 1999·Journal of Epidemiology and Community Health·C J EvansA J Lee
Aug 24, 1999·European Journal of Clinical Investigation·M E GschwandtnerH Ehringer
Sep 27, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M H Howlader, P D Smith
Dec 29, 2004·Journal of Vascular Surgery·Bo EklöfUNKNOWN American Venous Forum International Ad Hoc Committee for Revision of the CEAP Classification
Feb 25, 2005·The British Journal of Dermatology·A M Degiorgio-MillerS E Herrick
Citations
May 15, 2013·Journal des maladies vasculaires·N AuffretJ Constans
Feb 6, 2007·Journal des maladies vasculaires·N Danziger
Jul 26, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·W Y John Chen, Alan A Rogers
Sep 3, 2020·Vascular Medicine·Jiri Kanta, Anna Zavadakova
Jul 3, 2007·Biological Research for Nursing·Teresa J Kelechi, Yvonne Michel
Nov 21, 2007·British Journal of Community Nursing·Heather Middleton