PMID: 18200367Jan 18, 2008Paper

Correlation of tomographic findings with pulmonary function parameters in nonsmoking patients with idiopathic pulmonary fibrosis

Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Agnaldo José LopesJosé Manoel Jansen

Abstract

To correlate tomographic findings with pulmonary function parameters in patients with idiopathic pulmonary fibrosis (IPF). A cross-sectional study was carried out, in which 30 nonsmoking patients with IPF were evaluated. Using a semiquantitative scoring system, the following high-resolution computerized tomography (HRCT) findings were quantified: total interstitial disease (TID), reticular abnormality/honeycombing, and ground-glass opacity (GGO). The functional variables were measured by spirometry, forced oscillation technique (FOT), helium dilution method, as well as the single-breath method of measuring diffusion capacity of the lung for carbon monoxide (DLCO). Of the 30 patients studied, 18 were female, and 12 were male, with a mean age of 70.9 years. We found that TID and reticular abnormality and honeycombing correlated significantly (negative correlations) with the measurements of forced vital capacity (FVC), total lung capacity (TLC), DLCO, and dynamic respiratory compliance were found, as well as that GGO correlated significantly (and positively) with residual volume/TLC. The ratio of forced expiratory flow between 25 and 75% of FVC to FVC (FEF(25-75%)/FVC) correlated positively with TID, reticular abnormality/honeycom...Continue Reading

References

Dec 1, 1993·AJR. American Journal of Roentgenology·A U WellsD M Hansell
Feb 1, 1994·American Journal of Respiratory and Critical Care Medicine·D A SchwartzG W Hunninghake
Apr 1, 1997·American Journal of Respiratory and Critical Care Medicine·A U WellsD M Hansell
May 1, 1997·American Journal of Respiratory and Critical Care Medicine·A U WellsR M du Bois
Mar 6, 1998·Thorax·M J DohertyP M Calverley
Aug 12, 1998·American Journal of Respiratory and Critical Care Medicine·A XaubetR Rodriguez-Roisin
Jul 21, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J A NederL E Nery
Jul 21, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J A NederL E Nery
May 4, 2001·The European Respiratory Journal·U Costabel, T E King
Mar 29, 2003·American Journal of Respiratory and Critical Care Medicine·Athol U WellsDavid M Hansell
May 17, 2005·American Journal of Respiratory and Critical Care Medicine·David A LynchUNKNOWN Idiopathic Pulmonary Fibrosis Study Group
Jul 1, 2005·Radiology·David A LynchTalmadge E King
Jun 2, 2006·Proceedings of the American Thoracic Society·Shigeki Misumi, David A Lynch

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Citations

Jan 30, 2014·Nuclear Medicine Communications·Elaine Yuen Phin LeeJames Chung Man Ho
Jan 26, 2018·European Respiratory Review : an Official Journal of the European Respiratory Society·Laurent PlantierBruno Crestani

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