Correlation of total-body bone mineral content determined by dual-energy X-ray absorptiometry with bone mineral density determined by peripheral quantitative computed tomography

Academic Radiology
M RevillaH Rico

Abstract

We sought to determine the value of peripheral quantitative computed tomography (pQCT) in measuring bone mineral density. In 50 healthy, eugonodal premenopausal women, we correlated measurements of total bone mineral content (BMCTB), made with dual-energy X-ray absorptiometry (DXA), and bone mineral density, determined by pQCT. The partial correlations, adjusted for weight and age, between BMCTB and cortical bone density, total bone density, and trabecular bone density were .71 (p < .0001), .63 (p < .0001), and .32 (p < .05), respectively. These results and the advantages of pQCT--providing precise bone density determinations for trabecular and compact bone separately, having a high spatial resolution that allows a "compartmental" analysis of bone structure, having a low coefficient of variation, and having a minimal radiation dose (< 5 mrem)--confirm the adequacy of using this method for bone mass studies.

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Citations

Feb 7, 1998·Spine·L L Seeger
Nov 23, 2000·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·T N HangartnerV Matkovic
Sep 11, 2012·Academic Radiology·Wei-Liang TayAlvin Choong-Meng Ng
Dec 6, 2006·The Tohoku Journal of Experimental Medicine·Takahiko NoharaAkira Ohta

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