PMID: 590835Oct 1, 1977

Correlation of variations in intraluminal pressure and potential differences in the perfused colen

Gut
J G PostaireN Van Houtte

Abstract

To investigate the nature of variations in the large intestine potential differences, a continuous perfusion of isotonic saline was carried out in the colon of 14 rats. Intraluminal pressure and potential differences between the lumen and the peritoneal cavity were continuously and simultaneously recorded, while impedance of the system and respiration were also constantly monitored. To obtain a quantitative evaluation of the data, Fast Fouier Transform was performed on the signals and their derivatives which were auto- and cross-correlated. While there was no obvious relation between pressure and potential in the unperfused colon, there was clear visual qualirative evidence that, during steady state conditions of perfusion, an increase in intraluminal pressure was accompanied by a decrease in potential differences, while impedance of the recording system remained unchanged. Computer analysis disclosed four narrow ranges of stable frequencies for both pressure and potential. They were centred around 0-3, 1-75, 10-7, and 75 cycles per minute, the latter being synchronous with respiration. It is concluded that the variations of potential differences recorded during perfusion, a well-know phenomenon, are not electrical artefacts: t...Continue Reading

References

Sep 1, 1975·Medical & Biological Engineering·J G PostaireJ Gerard
Aug 1, 1974·Journal of Applied Physiology·A ChauveJ L Sasseville
Jul 1, 1971·The American Journal of Physiology·J F White, W M Armstrong
Feb 1, 1968·The Journal of Physiology·C J Edmonds, J Marriott
Jun 1, 1969·Proceedings of the Society for Experimental Biology and Medicine·K M Hanson, F T Moore
Feb 1, 1959·The Journal of Clinical Investigation·I L COOPERSTEIN, S K BROCKMAN

Citations

Nov 1, 1978·Bulletin of Environmental Contamination and Toxicology·J F Narbonne

Related Concepts

Taenia Coli
Resting Potentials
Perfusion

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