Correlations between computed tomography and positron emission tomography/computed tomography findings and pathology in 6 cases of pulmonary epithelioid angiosarcoma

Medicine
Xinguan YangYubao Guan

Abstract

Previous studies on primary pulmonary epithelioid angiosarcoma (PEA) have been mostly clinical or pathological case reports. We here summarize findings from computed tomography (CT) and positron emission tomography/computed tomography (PET/CT) analyses of PEA to improve the diagnosis and differentiation of this rare tumor.We conducted a retrospective analysis of the clinical findings, radiological imaging, and pathological findings of 6 cases of primary PEA confirmed by surgery, biopsy, and pathology. All cases were evaluated by CT and x-ray prior to surgery, and 2 cases were further examined by PET/CT.CT images indicated maximum tumor diameters of 2.4 to 9.8 cm and inhomogeneous density, with 1 case exhibiting nodular calcification. Contrast-enhanced CT revealed inhomogeneous enhancement with visible necrosis in all 6 cases, while 3 cases had hilar and mediastinal lymph node metastasis. Five cases displayed extensive tumor involvement with extension into the chest wall, mild-to-moderate levels of pleural effusion, and varying degrees of volume loss in the corresponding hemithorax. One case had limited pleural thickening and invasion. Preoperative PET/CT of 1 case revealed abnormal fluorine-18 fluorodeoxyglucose (F-FDG) uptake ...Continue Reading

References

Jan 25, 2006·Asian Cardiovascular & Thoracic Annals·Cemal OzcelikZerrin Ozcelik
Jun 15, 2010·Heart, Lung & Circulation·Gerardo Andres Obeso CarilloJose Luis Garcia Tejedor
Oct 19, 2010·Annals of Diagnostic Pathology·Naobumi TochigiHitoshi Tsuda
May 23, 2012·Pathology International·Chun-Fan YangI-Ping Chiang
May 10, 2013·Clinical Nuclear Medicine·Giorgio TregliaPaolo Graziano
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Nov 20, 2015·The Tohoku Journal of Experimental Medicine·Ikuko ShimabukuroHiroshi Mukae

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