Correlations between obstructive sleep apnea and adenotonsillar hypertrophy in children of different weight status

Scientific Reports
Jing WangXiangdong Tang

Abstract

The present study aimed to evaluate the relationship between OSA and adenotonsillar size in children of different weight status. A total of 451 patients aged 2-13 years with suspected OSA were retrospectively enrolled in the study. Correlations between the apnea-hypopnea index (AHI) and adenotonsillar size in different weight status were investigated. The adenoidal/nasopharyngeal (A/N) ratio of underweight children was significantly higher than that of normal-weight children (P = 0.027). Both adenoid and tonsil size were positively correlated with logAHI in children of normal weight (r = 0.210, P = 0.001; and r = 0.212, P = 0.001) but uncorrelated in the other groups. Gender (OR = 1.49, 95% CI: 1.01-2.20, P = 0.043), obese (OR = 1.93, 95% CI: 1.10-3.40, P = 0.012), A/N ratio (OR = 1.55, 95% CI: 1.28-1.88, P < 0.001) and tonsil size (OR = 1.36, 95% CI: 1.18-1.57, P < 0.001) were all associated with the severity of OSA. Adenotonsillar hypertrophy contributed to OSA in normal-weight children. In children of abnormal weight, instead of treatment for adenotonsillar hypertrophy, appropriate treatments for other factors are required.

References

Sep 1, 1979·AJR. American Journal of Roentgenology·M FujiokaB R Girdany
Aug 1, 1987·International Journal of Pediatric Otorhinolaryngology·L BrodskyJ F Stanievich
May 6, 1999·American Journal of Respiratory and Critical Care Medicine·S RedlineG Graham
Jan 10, 2002·American Journal of Respiratory and Critical Care Medicine·Raanan ArensAllan I Pack
Feb 20, 2002·International Journal of Pediatric Otorhinolaryngology·Joseph E KerschnerTom B Rice
May 23, 2002·American Journal of Respiratory and Critical Care Medicine·Raouf S AminSteven R Daniels
Nov 8, 2002·American Journal of Respiratory and Critical Care Medicine·Atul MalhotraDavid P White
Oct 3, 2007·Pediatrics·Ohad RonenGiora Pillar
Jan 5, 2008·American Journal of Respiratory and Critical Care Medicine·Raouf AminStephen Daniels
Feb 6, 2008·Proceedings of the American Thoracic Society·Julie C Lumeng, Ronald D Chervin
May 2, 2008·The European Respiratory Journal·I AlmendrosR Farré
Mar 7, 2009·Obesity·Stijn L VerhulstKristine Desager
Nov 3, 2009·The Journal of Craniofacial Surgery·Kwamena Amonoo-KuofiSusanna E J Leighton
May 8, 2010·American Journal of Respiratory and Critical Care Medicine·Rakesh BhattacharjeeDavid Gozal
Oct 12, 2010·American Journal of Respiratory and Critical Care Medicine·Raanan ArensKeivan Shifteh
Oct 23, 2010·Pediatric Pulmonology·Rakesh BhattacharjeeDavid Gozal
Apr 16, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jennifer Nolan, Scott E Brietzke
Jun 17, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Peter S RolandUNKNOWN American Academy of Otolaryngology—Head and Neck Surgery Foundation
Jan 25, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·K-T KangW-C Hsu
Oct 2, 2012·International Journal of Pediatric Otorhinolaryngology·Mitsuhiko TagayaTsutomu Nakashima
Oct 16, 2012·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Richard B BerryUNKNOWN American Academy of Sleep Medicine
Nov 7, 2015·The European Respiratory Journal·Athanasios G KaditisStijn Verhulst
Apr 27, 2016·Obesity·Asheley Cockrell SkinnerJoseph A Skelton
Feb 12, 2017·Paediatric Respiratory Reviews·David G IngramBrian F Birnbaum
Mar 6, 2018·The Journal of Pediatrics·Annelies Van EyckKim Van Hoorenbeeck

❮ Previous
Next ❯

Citations

Nov 17, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Courtney JohnsonRon B Mitchell

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine
Ari ShechterSleep AHEAD Research Group of the Look AHEAD Research Group
International Journal of Obesity : Journal of the International Association for the Study of Obesity
K-T KangW-C Hsu
© 2021 Meta ULC. All rights reserved